Immune response, smoking, and lung cancer: a systematic review

Here we review the role of innate and adaptive immunity at ascending lung cancer stages in smoking and non-smoking patients. T cell activity and the expression of pro-inflammatory cytokines were found to be elevated in smokers. As a consequence, smoking has been identified as a significant risk fact...

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Bibliographic Details
Main Authors: V. Yu. Buslaev, A. V. Minin, M. V. Katanakhova, A. V. Shabaldin
Format: Article
Language:Russian
Published: Kemerovo State Medical University 2024-09-01
Series:Фундаментальная и клиническая медицина
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Online Access:https://fcm.kemsmu.ru/jour/article/view/904
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Summary:Here we review the role of innate and adaptive immunity at ascending lung cancer stages in smoking and non-smoking patients. T cell activity and the expression of pro-inflammatory cytokines were found to be elevated in smokers. As a consequence, smoking has been identified as a significant risk factor promoting lung carcinogenesis. Further experimental research in this area will allow the development of novel diagnostic approaches, including circulating biomarkers and personalised medicine.
ISSN:2500-0764
2542-0941