Over-the-counter antibiotic dispensing by pharmacies: a standardised patient study in Udupi district, India

Background Antimicrobial resistance is a global health emergency, and one of the contributing factors is overuse and misuse of antibiotics. India is one of the world’s largest consumers of antibiotics, and inappropriate use is potentially widespread. This study aimed to use standardised patients (SP...

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Main Authors: Amrita Daftary, Madhukar Pai, Vaidehi Nafade, Sophie Huddart, Giorgia Sulis, Sonal Sekhar Miraj, Kavitha Saravu
Format: Article
Language:English
Published: BMJ Publishing Group 2019-12-01
Series:BMJ Global Health
Online Access:https://gh.bmj.com/content/4/6/e001869.full
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author Amrita Daftary
Madhukar Pai
Vaidehi Nafade
Sophie Huddart
Giorgia Sulis
Sonal Sekhar Miraj
Kavitha Saravu
author_facet Amrita Daftary
Madhukar Pai
Vaidehi Nafade
Sophie Huddart
Giorgia Sulis
Sonal Sekhar Miraj
Kavitha Saravu
author_sort Amrita Daftary
collection DOAJ
description Background Antimicrobial resistance is a global health emergency, and one of the contributing factors is overuse and misuse of antibiotics. India is one of the world’s largest consumers of antibiotics, and inappropriate use is potentially widespread. This study aimed to use standardised patients (SPs) to measure over-the-counter antibiotic dispensing in one region.Methods Three adults from the local community in Udupi, India, were recruited and trained as SPs. Three conditions, in both adults and children, were considered: diarrhoea, upper respiratory tract infection and acute fever. Adult SPs were used as proxies for the paediatric cases.Results A total of 1522 SP interactions were successfully completed from 279 pharmacies. The proportion of SP interactions resulting in the provision of an antibiotic was 4.34% (95% CI 3.04% to 6.08%) for adult SPs and 2.89% (95% CI 1.8% to 4.4%) for child SPs. In the model, referral to another provider was associated with an OR 0.38 (95% CI 0.18 to 0.79), the number of questions asked was associated with an OR 1.54 (95% CI 1.30 to 1.84) and an SP–pharmacist interaction lasting longer than 3 min was associated with an OR 3.03 (95% CI 1.11 to 8.27) as compared with an interaction lasting less than 1 min.Conclusion Over-the-counter antibiotic dispensing rate was low in Udupi district and substantially lower than previously published SP studies in other regions of India. Dispensing was lowest when pharmacies referred to a doctor, and higher when pharmacies asked more questions or spent more time with clients.
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spelling doaj-art-5627ea3de77045bda12d9abc6c76adc82025-08-20T02:08:46ZengBMJ Publishing GroupBMJ Global Health2059-79082019-12-014610.1136/bmjgh-2019-001869Over-the-counter antibiotic dispensing by pharmacies: a standardised patient study in Udupi district, IndiaAmrita Daftary0Madhukar Pai1Vaidehi Nafade2Sophie Huddart3Giorgia Sulis4Sonal Sekhar Miraj5Kavitha Saravu6Centre for the AIDS Programme of Research, Durban, KwaZulu-Natal, South AfricaMcGill International TB Centre, McGill University, Montreal, Québec, CanadaEpidemiology and Biostatistics, McGill University, Montreal, Québec, CanadaEpidemiology & Biostatistics, McGill University, Montreal, Quebec, CanadaDepartment of Epidemiology, Biostatistics and Occupational Health, McGill University, Montreal, Québec, CanadaDepartment of Pharmacy Parctice, Manipal College of Pharmaceutical Sciences, Manipal Academy of Higher Education, Manipal, Karnataka, IndiaDepartment of Infectious Diseases, Kasturba Medical College Manipal, Manipal, Karnataka, IndiaBackground Antimicrobial resistance is a global health emergency, and one of the contributing factors is overuse and misuse of antibiotics. India is one of the world’s largest consumers of antibiotics, and inappropriate use is potentially widespread. This study aimed to use standardised patients (SPs) to measure over-the-counter antibiotic dispensing in one region.Methods Three adults from the local community in Udupi, India, were recruited and trained as SPs. Three conditions, in both adults and children, were considered: diarrhoea, upper respiratory tract infection and acute fever. Adult SPs were used as proxies for the paediatric cases.Results A total of 1522 SP interactions were successfully completed from 279 pharmacies. The proportion of SP interactions resulting in the provision of an antibiotic was 4.34% (95% CI 3.04% to 6.08%) for adult SPs and 2.89% (95% CI 1.8% to 4.4%) for child SPs. In the model, referral to another provider was associated with an OR 0.38 (95% CI 0.18 to 0.79), the number of questions asked was associated with an OR 1.54 (95% CI 1.30 to 1.84) and an SP–pharmacist interaction lasting longer than 3 min was associated with an OR 3.03 (95% CI 1.11 to 8.27) as compared with an interaction lasting less than 1 min.Conclusion Over-the-counter antibiotic dispensing rate was low in Udupi district and substantially lower than previously published SP studies in other regions of India. Dispensing was lowest when pharmacies referred to a doctor, and higher when pharmacies asked more questions or spent more time with clients.https://gh.bmj.com/content/4/6/e001869.full
spellingShingle Amrita Daftary
Madhukar Pai
Vaidehi Nafade
Sophie Huddart
Giorgia Sulis
Sonal Sekhar Miraj
Kavitha Saravu
Over-the-counter antibiotic dispensing by pharmacies: a standardised patient study in Udupi district, India
BMJ Global Health
title Over-the-counter antibiotic dispensing by pharmacies: a standardised patient study in Udupi district, India
title_full Over-the-counter antibiotic dispensing by pharmacies: a standardised patient study in Udupi district, India
title_fullStr Over-the-counter antibiotic dispensing by pharmacies: a standardised patient study in Udupi district, India
title_full_unstemmed Over-the-counter antibiotic dispensing by pharmacies: a standardised patient study in Udupi district, India
title_short Over-the-counter antibiotic dispensing by pharmacies: a standardised patient study in Udupi district, India
title_sort over the counter antibiotic dispensing by pharmacies a standardised patient study in udupi district india
url https://gh.bmj.com/content/4/6/e001869.full
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