Impact of Vitamin D Deficiency on Iron Deficiency Anemia
Two important health problems are iron deficiency anemia and vitamin D deficiency, as well as the ability to cope with acute and chronic diseases, because iron and vitamin D are the main elements of physiological functions in the human body. Recent studies have indicated that generalized IDA in bot...
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Koya University
2025-08-01
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| Series: | ARO-The Scientific Journal of Koya University |
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| Online Access: | https://aro.koyauniversity.org/index.php/aro/article/view/1980 |
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| author | Sleman Y. Omar Awat H. Awla Musher I. Salih Badinan J. Hamadamin |
| author_facet | Sleman Y. Omar Awat H. Awla Musher I. Salih Badinan J. Hamadamin |
| author_sort | Sleman Y. Omar |
| collection | DOAJ |
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Two important health problems are iron deficiency anemia and vitamin D deficiency, as well as the ability to cope with acute and chronic diseases, because iron and vitamin D are the main elements of physiological functions in the human body. Recent studies have indicated that generalized IDA in both healthy and diseased populations may be associated with inadequate levels of VD. The research comprised 132 participants, 65 with IDA and 67 controls, the study was conducted in a competent cross-sectional design, between the two groups matched by age and gender. The laboratory findings included the study of blood indices. Ferritin, iron, hemoglobin, mean corpuscular volume, red cell distribution width, and VD levels were measured for each participant. Iron metabolism markers showed highly significant variations between the groups. Patients with IDA exhibited considerably lower levels of iron indicators than the healthy control group, except for total iron binding capacity (TIBC), which was increased among the patients. The normal control group showed substantially higher serum VD levels than patients with iron deficient anemia (p < 0.035). This distinction suggests a high positive link between VD levels and iron metabolism markers, except for TIBC, which exhibited a negative correlation. The results showed a significant correlation between VD levels and several iron metabolism markers in the research participants. This suggests that VD may affect how iron is metabolized and help treat IDA. To fully understand the underlying mechanisms and any therapeutic benefit, further research is needed.
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| format | Article |
| id | doaj-art-5626f48958af408ba5039b7eeb68430f |
| institution | Kabale University |
| issn | 2410-9355 2307-549X |
| language | English |
| publishDate | 2025-08-01 |
| publisher | Koya University |
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| series | ARO-The Scientific Journal of Koya University |
| spelling | doaj-art-5626f48958af408ba5039b7eeb68430f2025-08-20T03:36:38ZengKoya UniversityARO-The Scientific Journal of Koya University2410-93552307-549X2025-08-0113210.14500/aro.11980Impact of Vitamin D Deficiency on Iron Deficiency AnemiaSleman Y. Omar0https://orcid.org/0000-0002-9796-8063Awat H. Awla1https://orcid.org/0000-0002-9796-8063Musher I. Salih2https://orcid.org/0000-0002-3702-4060Badinan J. Hamadamin3https://orcid.org/0000-0001-5690-2132Department of Biology, College of science, University of Raparin, Sulaymaniyah, Kurdistan Region – F.R. IraqDepartment of Chemistry, College of science, University of Raparin, Sulaymaniyah, Kurdistan Region – F.R. IraqDepartment of Chemistry, Faculty of Science and Health, Koya University, Koya KOY45, Kurdistan Region – F.R. IraqDepartment of Biology, College of science, University of Raparin, Sulaymaniyah, Kurdistan Region – F.R. Iraq Two important health problems are iron deficiency anemia and vitamin D deficiency, as well as the ability to cope with acute and chronic diseases, because iron and vitamin D are the main elements of physiological functions in the human body. Recent studies have indicated that generalized IDA in both healthy and diseased populations may be associated with inadequate levels of VD. The research comprised 132 participants, 65 with IDA and 67 controls, the study was conducted in a competent cross-sectional design, between the two groups matched by age and gender. The laboratory findings included the study of blood indices. Ferritin, iron, hemoglobin, mean corpuscular volume, red cell distribution width, and VD levels were measured for each participant. Iron metabolism markers showed highly significant variations between the groups. Patients with IDA exhibited considerably lower levels of iron indicators than the healthy control group, except for total iron binding capacity (TIBC), which was increased among the patients. The normal control group showed substantially higher serum VD levels than patients with iron deficient anemia (p < 0.035). This distinction suggests a high positive link between VD levels and iron metabolism markers, except for TIBC, which exhibited a negative correlation. The results showed a significant correlation between VD levels and several iron metabolism markers in the research participants. This suggests that VD may affect how iron is metabolized and help treat IDA. To fully understand the underlying mechanisms and any therapeutic benefit, further research is needed. https://aro.koyauniversity.org/index.php/aro/article/view/1980AnemiaHemoglobin FerritinIron deficiencyVitamin D deficiency |
| spellingShingle | Sleman Y. Omar Awat H. Awla Musher I. Salih Badinan J. Hamadamin Impact of Vitamin D Deficiency on Iron Deficiency Anemia ARO-The Scientific Journal of Koya University Anemia Hemoglobin Ferritin Iron deficiency Vitamin D deficiency |
| title | Impact of Vitamin D Deficiency on Iron Deficiency Anemia |
| title_full | Impact of Vitamin D Deficiency on Iron Deficiency Anemia |
| title_fullStr | Impact of Vitamin D Deficiency on Iron Deficiency Anemia |
| title_full_unstemmed | Impact of Vitamin D Deficiency on Iron Deficiency Anemia |
| title_short | Impact of Vitamin D Deficiency on Iron Deficiency Anemia |
| title_sort | impact of vitamin d deficiency on iron deficiency anemia |
| topic | Anemia Hemoglobin Ferritin Iron deficiency Vitamin D deficiency |
| url | https://aro.koyauniversity.org/index.php/aro/article/view/1980 |
| work_keys_str_mv | AT slemanyomar impactofvitaminddeficiencyonirondeficiencyanemia AT awathawla impactofvitaminddeficiencyonirondeficiencyanemia AT musherisalih impactofvitaminddeficiencyonirondeficiencyanemia AT badinanjhamadamin impactofvitaminddeficiencyonirondeficiencyanemia |