No Relationship between Maternal Iron Status and Postpartum Depression in Two Samples in China

Maternal iron status is thought to be related to postpartum depressive symptoms. The purpose of the present study was to evaluate the relationship between pre- and postnatal maternal iron status and depressive symptoms in pilot (n=137) and confirmatory (n=567) samples of Chinese women. Iron status w...

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Main Authors: Rinat Armony-Sivan, Jie Shao, Ming Li, Gengli Zhao, Zhengyan Zhao, Guobing Xu, Min Zhou, Jianying Zhan, Yang Bian, Chai Ji, Xing Li, Yaping Jiang, Zhixiang Zhang, Blair J. Richards, Twila Tardif, Betsy Lozoff
Format: Article
Language:English
Published: Wiley 2012-01-01
Series:Journal of Pregnancy
Online Access:http://dx.doi.org/10.1155/2012/521431
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author Rinat Armony-Sivan
Jie Shao
Ming Li
Gengli Zhao
Zhengyan Zhao
Guobing Xu
Min Zhou
Jianying Zhan
Yang Bian
Chai Ji
Xing Li
Yaping Jiang
Zhixiang Zhang
Blair J. Richards
Twila Tardif
Betsy Lozoff
author_facet Rinat Armony-Sivan
Jie Shao
Ming Li
Gengli Zhao
Zhengyan Zhao
Guobing Xu
Min Zhou
Jianying Zhan
Yang Bian
Chai Ji
Xing Li
Yaping Jiang
Zhixiang Zhang
Blair J. Richards
Twila Tardif
Betsy Lozoff
author_sort Rinat Armony-Sivan
collection DOAJ
description Maternal iron status is thought to be related to postpartum depressive symptoms. The purpose of the present study was to evaluate the relationship between pre- and postnatal maternal iron status and depressive symptoms in pilot (n=137) and confirmatory (n=567) samples of Chinese women. Iron status was evaluated at mid- and late pregnancy and 3 days postpartum. The Edinburgh Postnatal Depression Scale (EPDS) was used to assess maternal postpartum depression 24–48 hours after delivery and 6 weeks later. In the pilot sample, correlations between early- and late-pregnancy maternal Hb and EPDS scores at 6 weeks were r=0.07 and −0.01, respectively (nonsignificant). In the confirmatory sample, the correlations between maternal iron measures (Hb, MCV, ZPP, ferritin, sTfR, and sTfR Index) in mid- or late pregnancy or 3 days postpartum and EPDS scores shortly after delivery or at 6 weeks were also low (r values < 0.10). EPDS scores in anemic and nonanemic mothers did not differ, regardless of sample or timing of maternal iron status assessment. In addition, women with or without possible PPD were similar in iron status in both samples. Thus, there was no relationship between maternal iron status and postpartum depression in these samples.
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publishDate 2012-01-01
publisher Wiley
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spelling doaj-art-5624e701144d4141ab34cc0c02db951d2025-08-20T02:04:58ZengWileyJournal of Pregnancy2090-27272090-27352012-01-01201210.1155/2012/521431521431No Relationship between Maternal Iron Status and Postpartum Depression in Two Samples in ChinaRinat Armony-Sivan0Jie Shao1Ming Li2Gengli Zhao3Zhengyan Zhao4Guobing Xu5Min Zhou6Jianying Zhan7Yang Bian8Chai Ji9Xing Li10Yaping Jiang11Zhixiang Zhang12Blair J. Richards13Twila Tardif14Betsy Lozoff15Center for Human Growth and Development, University of Michigan, Ann Arbor, MI 48109, USADepartment of Child Health Care, Children's Hospital Zhejiang University School of Medicine, Hangzhou 310003, ChinaDepartment of Pediatrics, Peking University First Hospital, Beijing 100034, ChinaWomen’s and Children’s Health Center, Peking University, Beijing 100034, ChinaDepartment of Child Health Care, Children's Hospital Zhejiang University School of Medicine, Hangzhou 310003, ChinaDepartment of Clinical Laboratory, Peking University First Hospital, Beijing 100034, ChinaWomen’s and Children’s Health Center, Peking University, Beijing 100034, ChinaDepartment of Child Health Care, Children's Hospital Zhejiang University School of Medicine, Hangzhou 310003, ChinaDepartment of Pediatrics, Peking University First Hospital, Beijing 100034, ChinaDepartment of Child Health Care, Children's Hospital Zhejiang University School of Medicine, Hangzhou 310003, ChinaDepartment of Pediatrics, Peking University First Hospital, Beijing 100034, ChinaDepartment of Clinical Laboratory, Peking University First Hospital, Beijing 100034, ChinaDepartment of Pediatrics, Peking University First Hospital, Beijing 100034, ChinaCenter for Human Growth and Development, University of Michigan, Ann Arbor, MI 48109, USACenter for Human Growth and Development, University of Michigan, Ann Arbor, MI 48109, USACenter for Human Growth and Development, University of Michigan, Ann Arbor, MI 48109, USAMaternal iron status is thought to be related to postpartum depressive symptoms. The purpose of the present study was to evaluate the relationship between pre- and postnatal maternal iron status and depressive symptoms in pilot (n=137) and confirmatory (n=567) samples of Chinese women. Iron status was evaluated at mid- and late pregnancy and 3 days postpartum. The Edinburgh Postnatal Depression Scale (EPDS) was used to assess maternal postpartum depression 24–48 hours after delivery and 6 weeks later. In the pilot sample, correlations between early- and late-pregnancy maternal Hb and EPDS scores at 6 weeks were r=0.07 and −0.01, respectively (nonsignificant). In the confirmatory sample, the correlations between maternal iron measures (Hb, MCV, ZPP, ferritin, sTfR, and sTfR Index) in mid- or late pregnancy or 3 days postpartum and EPDS scores shortly after delivery or at 6 weeks were also low (r values < 0.10). EPDS scores in anemic and nonanemic mothers did not differ, regardless of sample or timing of maternal iron status assessment. In addition, women with or without possible PPD were similar in iron status in both samples. Thus, there was no relationship between maternal iron status and postpartum depression in these samples.http://dx.doi.org/10.1155/2012/521431
spellingShingle Rinat Armony-Sivan
Jie Shao
Ming Li
Gengli Zhao
Zhengyan Zhao
Guobing Xu
Min Zhou
Jianying Zhan
Yang Bian
Chai Ji
Xing Li
Yaping Jiang
Zhixiang Zhang
Blair J. Richards
Twila Tardif
Betsy Lozoff
No Relationship between Maternal Iron Status and Postpartum Depression in Two Samples in China
Journal of Pregnancy
title No Relationship between Maternal Iron Status and Postpartum Depression in Two Samples in China
title_full No Relationship between Maternal Iron Status and Postpartum Depression in Two Samples in China
title_fullStr No Relationship between Maternal Iron Status and Postpartum Depression in Two Samples in China
title_full_unstemmed No Relationship between Maternal Iron Status and Postpartum Depression in Two Samples in China
title_short No Relationship between Maternal Iron Status and Postpartum Depression in Two Samples in China
title_sort no relationship between maternal iron status and postpartum depression in two samples in china
url http://dx.doi.org/10.1155/2012/521431
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