Thyrotropin exacerbates insulin resistance by triggering macrophage inflammation in subclinical hypothyroidism
Abstract In subclinical hypothyroidism, the levels of serum thyroid-stimulating hormone (TSH) are positively correlated with insulin resistance; however, the precise mechanism is unclear. Except for thyroid follicular epithelial cells, macrophages express the highest levels of TSHR. Thus, we specula...
Saved in:
| Main Authors: | Haihong Zhang, Zekun Zeng, Yan Liu, Wenfang Zheng, Jianling Wang, Yao Yao, Yanan Wang, Meiju Ji, Peng Hou |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nature Publishing Group
2025-06-01
|
| Series: | Experimental and Molecular Medicine |
| Online Access: | https://doi.org/10.1038/s12276-025-01478-1 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Subclinical hypothyroidism: treat or watch?
by: I. A. Tsanava, et al.
Published: (2021-03-01) -
EPIDEMIOLOGICAL CHARACTERISTICS OF SUBCLINICAL HYPOTHYROIDISM
by: Inoyatova Nigina Azizovna, et al.
Published: (2024-12-01) -
Influence of Gut Microbiota on Subclinical Inflammation and Insulin Resistance
by: Bruno Melo Carvalho, et al.
Published: (2013-01-01) -
Association of insulin-like growth factor 1 and metabolic parameters with mild subclinical hypothyroidism in obese boys
by: Jiang Xue, et al.
Published: (2025-05-01) -
Cardiovascular risk factors in patients with subclinical hypothyroidism
by: Pešić Milica, et al.
Published: (2007-01-01)