Systemic Toxicity of Intraperitoneal Vancomycin
Intraperitoneal vancomycin is used for empiric treatment of peritoneal dialysis peritonitis. It is dosed intermittently and a high systemic concentration is often achieved. Despite this, there are very few reports of systemic toxicity from intraperitoneal vancomycin. We report the course of a patien...
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| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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Wiley
2016-01-01
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| Series: | Case Reports in Nephrology |
| Online Access: | http://dx.doi.org/10.1155/2016/3968690 |
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| _version_ | 1832554419741261824 |
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| author | Teerath Kumar Iris Teo Brendan B. McCormick |
| author_facet | Teerath Kumar Iris Teo Brendan B. McCormick |
| author_sort | Teerath Kumar |
| collection | DOAJ |
| description | Intraperitoneal vancomycin is used for empiric treatment of peritoneal dialysis peritonitis. It is dosed intermittently and a high systemic concentration is often achieved. Despite this, there are very few reports of systemic toxicity from intraperitoneal vancomycin. We report the course of a patient who developed a drug reaction with eosinophilia and systemic symptoms (DRESS) syndrome after three weeks of intraperitoneal vancomycin. We review the literature and conclude that this is the first ever reported case of DRESS syndrome from intraperitoneal vancomycin. |
| format | Article |
| id | doaj-art-561439bfa1e04762962c1c8acfc880d9 |
| institution | Kabale University |
| issn | 2090-6641 2090-665X |
| language | English |
| publishDate | 2016-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Nephrology |
| spelling | doaj-art-561439bfa1e04762962c1c8acfc880d92025-02-03T05:51:31ZengWileyCase Reports in Nephrology2090-66412090-665X2016-01-01201610.1155/2016/39686903968690Systemic Toxicity of Intraperitoneal VancomycinTeerath Kumar0Iris Teo1Brendan B. McCormick2Division of Nephrology, Department of Medicine, University of Ottawa and The Ottawa Hospital, Ottawa, ON, CanadaDepartment of Pathology, University of Ottawa and The Ottawa Hospital, Ottawa, ON, CanadaDivision of Nephrology, Department of Medicine, University of Ottawa and The Ottawa Hospital, Ottawa, ON, CanadaIntraperitoneal vancomycin is used for empiric treatment of peritoneal dialysis peritonitis. It is dosed intermittently and a high systemic concentration is often achieved. Despite this, there are very few reports of systemic toxicity from intraperitoneal vancomycin. We report the course of a patient who developed a drug reaction with eosinophilia and systemic symptoms (DRESS) syndrome after three weeks of intraperitoneal vancomycin. We review the literature and conclude that this is the first ever reported case of DRESS syndrome from intraperitoneal vancomycin.http://dx.doi.org/10.1155/2016/3968690 |
| spellingShingle | Teerath Kumar Iris Teo Brendan B. McCormick Systemic Toxicity of Intraperitoneal Vancomycin Case Reports in Nephrology |
| title | Systemic Toxicity of Intraperitoneal Vancomycin |
| title_full | Systemic Toxicity of Intraperitoneal Vancomycin |
| title_fullStr | Systemic Toxicity of Intraperitoneal Vancomycin |
| title_full_unstemmed | Systemic Toxicity of Intraperitoneal Vancomycin |
| title_short | Systemic Toxicity of Intraperitoneal Vancomycin |
| title_sort | systemic toxicity of intraperitoneal vancomycin |
| url | http://dx.doi.org/10.1155/2016/3968690 |
| work_keys_str_mv | AT teerathkumar systemictoxicityofintraperitonealvancomycin AT iristeo systemictoxicityofintraperitonealvancomycin AT brendanbmccormick systemictoxicityofintraperitonealvancomycin |