Presentation and Management of Thyroid Involvement in Systemic and Primary Thyroid Lymphoma: A Case Series

This case series describes 4 female patients with thyroid lymphoma, including 3 primary thyroid lymphomas and 1 secondary thyroid involvement due to Burkitt lymphoma. Identified within a cohort of 878 lymphoma patients (2018–2022), primary thyroid lymphomas represented a 0.5% prevalence. Cervical ul...

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Main Authors: Marcos Tadashi Kakitani Toyoshima, Camila Regina Pereira Batista de Macedo, Isabelle Pinheiro Amaro de Magalhães, Rodrigo Dolphini Velasques, Ana O. Hoff
Format: Article
Language:English
Published: American College of Physicians 2025-06-01
Series:Annals of Internal Medicine: Clinical Cases
Online Access:https://www.acpjournals.org/doi/10.7326/aimcc.2024.1289
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author Marcos Tadashi Kakitani Toyoshima
Camila Regina Pereira Batista de Macedo
Isabelle Pinheiro Amaro de Magalhães
Rodrigo Dolphini Velasques
Ana O. Hoff
author_facet Marcos Tadashi Kakitani Toyoshima
Camila Regina Pereira Batista de Macedo
Isabelle Pinheiro Amaro de Magalhães
Rodrigo Dolphini Velasques
Ana O. Hoff
author_sort Marcos Tadashi Kakitani Toyoshima
collection DOAJ
description This case series describes 4 female patients with thyroid lymphoma, including 3 primary thyroid lymphomas and 1 secondary thyroid involvement due to Burkitt lymphoma. Identified within a cohort of 878 lymphoma patients (2018–2022), primary thyroid lymphomas represented a 0.5% prevalence. Cervical ultrasound, computed tomography, or magnetic resonance imaging revealed thyroid abnormalities. Fine-needle aspiration biopsy followed by biopsy confirmed diagnoses. Positron emission tomography with 18F-fluorodeoxyglucose (FDG-PET) highlighted metabolic activity correlating with aggressiveness. This series emphasizes the complementary roles of imaging and pathology in diagnosis and highlights the importance of a multidisciplinary approach to managing these rare malignancies.
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series Annals of Internal Medicine: Clinical Cases
spelling doaj-art-55ece51f5ffe4c6abfd0e092068b217f2025-08-20T02:07:46ZengAmerican College of PhysiciansAnnals of Internal Medicine: Clinical Cases2767-76642025-06-014610.7326/aimcc.2024.1289Presentation and Management of Thyroid Involvement in Systemic and Primary Thyroid Lymphoma: A Case SeriesMarcos Tadashi Kakitani Toyoshima0Camila Regina Pereira Batista de Macedo1Isabelle Pinheiro Amaro de Magalhães2Rodrigo Dolphini Velasques3Ana O. Hoff41Endocrine Oncology Unit, Instituto do Câncer do Estado de São Paulo Octávio Frias de Oliveira, Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil2Department of Endocrinology and Metabolism, Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil2Department of Endocrinology and Metabolism, Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil3Division of Hematology, Transfusion Medicine and Cell Therapy, Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil1Endocrine Oncology Unit, Instituto do Câncer do Estado de São Paulo Octávio Frias de Oliveira, Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo, São Paulo, BrazilThis case series describes 4 female patients with thyroid lymphoma, including 3 primary thyroid lymphomas and 1 secondary thyroid involvement due to Burkitt lymphoma. Identified within a cohort of 878 lymphoma patients (2018–2022), primary thyroid lymphomas represented a 0.5% prevalence. Cervical ultrasound, computed tomography, or magnetic resonance imaging revealed thyroid abnormalities. Fine-needle aspiration biopsy followed by biopsy confirmed diagnoses. Positron emission tomography with 18F-fluorodeoxyglucose (FDG-PET) highlighted metabolic activity correlating with aggressiveness. This series emphasizes the complementary roles of imaging and pathology in diagnosis and highlights the importance of a multidisciplinary approach to managing these rare malignancies.https://www.acpjournals.org/doi/10.7326/aimcc.2024.1289
spellingShingle Marcos Tadashi Kakitani Toyoshima
Camila Regina Pereira Batista de Macedo
Isabelle Pinheiro Amaro de Magalhães
Rodrigo Dolphini Velasques
Ana O. Hoff
Presentation and Management of Thyroid Involvement in Systemic and Primary Thyroid Lymphoma: A Case Series
Annals of Internal Medicine: Clinical Cases
title Presentation and Management of Thyroid Involvement in Systemic and Primary Thyroid Lymphoma: A Case Series
title_full Presentation and Management of Thyroid Involvement in Systemic and Primary Thyroid Lymphoma: A Case Series
title_fullStr Presentation and Management of Thyroid Involvement in Systemic and Primary Thyroid Lymphoma: A Case Series
title_full_unstemmed Presentation and Management of Thyroid Involvement in Systemic and Primary Thyroid Lymphoma: A Case Series
title_short Presentation and Management of Thyroid Involvement in Systemic and Primary Thyroid Lymphoma: A Case Series
title_sort presentation and management of thyroid involvement in systemic and primary thyroid lymphoma a case series
url https://www.acpjournals.org/doi/10.7326/aimcc.2024.1289
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