Presentation and Management of Thyroid Involvement in Systemic and Primary Thyroid Lymphoma: A Case Series

This case series describes 4 female patients with thyroid lymphoma, including 3 primary thyroid lymphomas and 1 secondary thyroid involvement due to Burkitt lymphoma. Identified within a cohort of 878 lymphoma patients (2018–2022), primary thyroid lymphomas represented a 0.5% prevalence. Cervical ul...

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Bibliographic Details
Main Authors: Marcos Tadashi Kakitani Toyoshima, Camila Regina Pereira Batista de Macedo, Isabelle Pinheiro Amaro de Magalhães, Rodrigo Dolphini Velasques, Ana O. Hoff
Format: Article
Language:English
Published: American College of Physicians 2025-06-01
Series:Annals of Internal Medicine: Clinical Cases
Online Access:https://www.acpjournals.org/doi/10.7326/aimcc.2024.1289
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Summary:This case series describes 4 female patients with thyroid lymphoma, including 3 primary thyroid lymphomas and 1 secondary thyroid involvement due to Burkitt lymphoma. Identified within a cohort of 878 lymphoma patients (2018–2022), primary thyroid lymphomas represented a 0.5% prevalence. Cervical ultrasound, computed tomography, or magnetic resonance imaging revealed thyroid abnormalities. Fine-needle aspiration biopsy followed by biopsy confirmed diagnoses. Positron emission tomography with 18F-fluorodeoxyglucose (FDG-PET) highlighted metabolic activity correlating with aggressiveness. This series emphasizes the complementary roles of imaging and pathology in diagnosis and highlights the importance of a multidisciplinary approach to managing these rare malignancies.
ISSN:2767-7664