Real‐world use of adjunctive perampanel for focal‐onset seizures in Italy: A mirroring clinical practice study of perampanel in adults and adolescents (AMPA)

Real‐world use of adjunctive perampanel for focal‐onset seizures in Italy: A mirroring clinical practice study of perampanel in adults and adolescents (AMPA)

Abstract Objective The AMPA study (Study 501; NCT04257604) was a multicenter, prospective, 12‐month observational study in Italy that evaluated the effectiveness and safety of adjunctive perampanel in patients with focal‐onset seizures (FOS), with or without focal to bilateral tonic–clonic seizures...

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Main Authors: Alfredo D'Aniello, Anna Teresa Giallonardo, Paolo Tinuper, Oriano Mecarelli, Umberto Aguglia, Giovanni Assenza, Antonio Gambardella, Maria Paola Canevini, Renato Scifo, Stefano Meletti, Valentina De Giorgis, Enrica Bonanni, Roberto Michelucci, Caterina Cerminara, Antonino Romeo, Federico Vigevano, Francesca Felicia Operto, Luciana Tramacere, Giancarlo Di Gennaro, Alfonso Iudice on behalf of the AMPA Study group, Leock Y. Ngo, Anna Patten, Anna Lisa Gentile, Andrea Pecori, Samantha Goldman
Format: Article
Language:English
Published: Wiley 2025-08-01
Series:Epilepsia Open
Subjects:
adjunctive therapy
anti‐seizure medication
epilepsy
focal to bilateral tonic–clonic seizures
low dose
older adults
Online Access:https://doi.org/10.1002/epi4.70068
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