Is Blood Alcohol Level a Good Predictor for Injury Severity Outcomes in Motor Vehicle Crash Victims?
Experimental studies in animals suggest that alcohol may influence pathophysiologic response to injury mechanisms. However, biological evidence for the alcohol-injury severity relationship provides conflicting results. The purpose of our retrospective cross-sectional study in 2,323 people was to as...
Saved in:
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2011-01-01
|
| Series: | Emergency Medicine International |
| Online Access: | http://dx.doi.org/10.1155/2011/616323 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1850227039094702080 |
|---|---|
| author | Bikaramjit Mann Ediriweera Desapriya Takeo Fujiwara Ian Pike |
| author_facet | Bikaramjit Mann Ediriweera Desapriya Takeo Fujiwara Ian Pike |
| author_sort | Bikaramjit Mann |
| collection | DOAJ |
| description | Experimental studies in animals suggest that alcohol may influence pathophysiologic response to injury mechanisms. However, biological evidence for the alcohol-injury severity relationship provides conflicting results. The purpose of our retrospective cross-sectional study in 2,323 people was to assess whether blood alcohol level (BAC) adversely influences injury severity in victims of motor vehicle collisions (MVCs). We found no difference in mortality OR 1.09 (0.73–1.62), or length of hospital stay, and a trend for lower ISS score was found in the high-alcohol group (P=0.052). Furthermore, the high-alcohol group demonstrated a lower adjusted rate of severe head injury OR 0.65 (0.48–0.87), chest injury OR 0.58 (0.42–0.80), and serious extremity injury OR 0.10 (0.01–0.76). The findings of our study do not demonstrate a dose-response relationship between alcohol consumption and injury severity in MVCs. This study implies that higher BAC may lead to less severe injuries, without impacting mortality or length of hospital stay, however, further research is required to elucidate the nature of this relationship. |
| format | Article |
| id | doaj-art-55e76677c6dd4db1a743ea7aa233a59a |
| institution | OA Journals |
| issn | 2090-2840 2090-2859 |
| language | English |
| publishDate | 2011-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Emergency Medicine International |
| spelling | doaj-art-55e76677c6dd4db1a743ea7aa233a59a2025-08-20T02:04:55ZengWileyEmergency Medicine International2090-28402090-28592011-01-01201110.1155/2011/616323616323Is Blood Alcohol Level a Good Predictor for Injury Severity Outcomes in Motor Vehicle Crash Victims?Bikaramjit Mann0Ediriweera Desapriya1Takeo Fujiwara2Ian Pike3Department of Medicine, Faculty of Medicine, University of Calgary, 1403-29 Street NW, Calgary, AB, T2N 2T9, CanadaBC Injury Research and Prevention Unit, L408-4480 Oak Street, Vancouver, BC, V6H 3V4, CanadaBC Injury Research and Prevention Unit, L408-4480 Oak Street, Vancouver, BC, V6H 3V4, CanadaBC Injury Research and Prevention Unit, L408-4480 Oak Street, Vancouver, BC, V6H 3V4, CanadaExperimental studies in animals suggest that alcohol may influence pathophysiologic response to injury mechanisms. However, biological evidence for the alcohol-injury severity relationship provides conflicting results. The purpose of our retrospective cross-sectional study in 2,323 people was to assess whether blood alcohol level (BAC) adversely influences injury severity in victims of motor vehicle collisions (MVCs). We found no difference in mortality OR 1.09 (0.73–1.62), or length of hospital stay, and a trend for lower ISS score was found in the high-alcohol group (P=0.052). Furthermore, the high-alcohol group demonstrated a lower adjusted rate of severe head injury OR 0.65 (0.48–0.87), chest injury OR 0.58 (0.42–0.80), and serious extremity injury OR 0.10 (0.01–0.76). The findings of our study do not demonstrate a dose-response relationship between alcohol consumption and injury severity in MVCs. This study implies that higher BAC may lead to less severe injuries, without impacting mortality or length of hospital stay, however, further research is required to elucidate the nature of this relationship.http://dx.doi.org/10.1155/2011/616323 |
| spellingShingle | Bikaramjit Mann Ediriweera Desapriya Takeo Fujiwara Ian Pike Is Blood Alcohol Level a Good Predictor for Injury Severity Outcomes in Motor Vehicle Crash Victims? Emergency Medicine International |
| title | Is Blood Alcohol Level a Good Predictor for Injury Severity Outcomes in Motor Vehicle Crash Victims? |
| title_full | Is Blood Alcohol Level a Good Predictor for Injury Severity Outcomes in Motor Vehicle Crash Victims? |
| title_fullStr | Is Blood Alcohol Level a Good Predictor for Injury Severity Outcomes in Motor Vehicle Crash Victims? |
| title_full_unstemmed | Is Blood Alcohol Level a Good Predictor for Injury Severity Outcomes in Motor Vehicle Crash Victims? |
| title_short | Is Blood Alcohol Level a Good Predictor for Injury Severity Outcomes in Motor Vehicle Crash Victims? |
| title_sort | is blood alcohol level a good predictor for injury severity outcomes in motor vehicle crash victims |
| url | http://dx.doi.org/10.1155/2011/616323 |
| work_keys_str_mv | AT bikaramjitmann isbloodalcohollevelagoodpredictorforinjuryseverityoutcomesinmotorvehiclecrashvictims AT ediriweeradesapriya isbloodalcohollevelagoodpredictorforinjuryseverityoutcomesinmotorvehiclecrashvictims AT takeofujiwara isbloodalcohollevelagoodpredictorforinjuryseverityoutcomesinmotorvehiclecrashvictims AT ianpike isbloodalcohollevelagoodpredictorforinjuryseverityoutcomesinmotorvehiclecrashvictims |