Recent advances in microalgae-driven carbon capture, utilization, and storage: Strain engineering through adaptive laboratory evolution and microbiome optimization

The potential of microalgae as a biological resource for carbon capture, utilization, and storage (CCUS) has been extensively discussed. Although genetic engineering methods have been employed to improve microalgal phenotypes, they often face challenges related to public concerns regarding genetical...

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Main Authors: Zhongshi He, Jing Wang, Yantao Li
Format: Article
Language:English
Published: KeAi Communications Co., Ltd. 2025-03-01
Series:Green Carbon
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Online Access:http://www.sciencedirect.com/science/article/pii/S2950155524000818
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author Zhongshi He
Jing Wang
Yantao Li
author_facet Zhongshi He
Jing Wang
Yantao Li
author_sort Zhongshi He
collection DOAJ
description The potential of microalgae as a biological resource for carbon capture, utilization, and storage (CCUS) has been extensively discussed. Although genetic engineering methods have been employed to improve microalgal phenotypes, they often face challenges related to public concerns regarding genetically modified organisms. By contrast, adaptive laboratory evolution (ALE) and microbiome optimization have emerged as promising non-genetic modification strategies, with notable success in bacterial models. In microalgae, ALE has been employed to improve resilience against varying environmental and stress factors and increase carbon capture efficiency, and for the production of valuable bioproducts through gradual accumulation of beneficial mutations following manual or automated selection. Furthermore, advancements in the understanding of microbial symbiotic relationships in the phycosphere have facilitated microbiome optimization in microalgal cultivation systems, significantly improving their functionality and productivity. In this study, we provide a comprehensive overview of the latest advancements in ALE and microbiome optimization of microalgae for CCUS across different carbon emission scenarios, including flue gas, biogas, wastewater, and landfill leachate. We further discuss the current challenges and future directions for the integration of ALE with microbiome optimization, focusing on the potential synergies of these methodologies. Overall, ALE and microbiome optimization are promising approaches to direct microalgae for environmental and industrial CCUS applications, thereby reducing global carbon emissions and addressing climate change challenges.
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spelling doaj-art-55e75b345d724fa08bd688f0150107962025-08-20T03:42:27ZengKeAi Communications Co., Ltd.Green Carbon2950-15552025-03-0131749910.1016/j.greenca.2024.10.001Recent advances in microalgae-driven carbon capture, utilization, and storage: Strain engineering through adaptive laboratory evolution and microbiome optimizationZhongshi He0Jing Wang1Yantao Li2Institute of Marine and Environmental Technology, University of Maryland Center for Environmental Science, Baltimore, MD 21202, USAInstitute of Marine and Environmental Technology, University of Maryland Center for Environmental Science, Baltimore, MD 21202, USAInstitute of Marine and Environmental Technology, University of Maryland Center for Environmental Science, Baltimore, MD 21202, USA; Department of Marine Biotechnology, University of Maryland Baltimore County, Baltimore, MD 21202, USA; Corresponding author.The potential of microalgae as a biological resource for carbon capture, utilization, and storage (CCUS) has been extensively discussed. Although genetic engineering methods have been employed to improve microalgal phenotypes, they often face challenges related to public concerns regarding genetically modified organisms. By contrast, adaptive laboratory evolution (ALE) and microbiome optimization have emerged as promising non-genetic modification strategies, with notable success in bacterial models. In microalgae, ALE has been employed to improve resilience against varying environmental and stress factors and increase carbon capture efficiency, and for the production of valuable bioproducts through gradual accumulation of beneficial mutations following manual or automated selection. Furthermore, advancements in the understanding of microbial symbiotic relationships in the phycosphere have facilitated microbiome optimization in microalgal cultivation systems, significantly improving their functionality and productivity. In this study, we provide a comprehensive overview of the latest advancements in ALE and microbiome optimization of microalgae for CCUS across different carbon emission scenarios, including flue gas, biogas, wastewater, and landfill leachate. We further discuss the current challenges and future directions for the integration of ALE with microbiome optimization, focusing on the potential synergies of these methodologies. Overall, ALE and microbiome optimization are promising approaches to direct microalgae for environmental and industrial CCUS applications, thereby reducing global carbon emissions and addressing climate change challenges.http://www.sciencedirect.com/science/article/pii/S2950155524000818MicroalgaeCarbon capture, utilization, and storage (CCUS)Strain engineeringAdaptive laboratory evolutionMicrobiome optimization
spellingShingle Zhongshi He
Jing Wang
Yantao Li
Recent advances in microalgae-driven carbon capture, utilization, and storage: Strain engineering through adaptive laboratory evolution and microbiome optimization
Green Carbon
Microalgae
Carbon capture, utilization, and storage (CCUS)
Strain engineering
Adaptive laboratory evolution
Microbiome optimization
title Recent advances in microalgae-driven carbon capture, utilization, and storage: Strain engineering through adaptive laboratory evolution and microbiome optimization
title_full Recent advances in microalgae-driven carbon capture, utilization, and storage: Strain engineering through adaptive laboratory evolution and microbiome optimization
title_fullStr Recent advances in microalgae-driven carbon capture, utilization, and storage: Strain engineering through adaptive laboratory evolution and microbiome optimization
title_full_unstemmed Recent advances in microalgae-driven carbon capture, utilization, and storage: Strain engineering through adaptive laboratory evolution and microbiome optimization
title_short Recent advances in microalgae-driven carbon capture, utilization, and storage: Strain engineering through adaptive laboratory evolution and microbiome optimization
title_sort recent advances in microalgae driven carbon capture utilization and storage strain engineering through adaptive laboratory evolution and microbiome optimization
topic Microalgae
Carbon capture, utilization, and storage (CCUS)
Strain engineering
Adaptive laboratory evolution
Microbiome optimization
url http://www.sciencedirect.com/science/article/pii/S2950155524000818
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AT jingwang recentadvancesinmicroalgaedrivencarboncaptureutilizationandstoragestrainengineeringthroughadaptivelaboratoryevolutionandmicrobiomeoptimization
AT yantaoli recentadvancesinmicroalgaedrivencarboncaptureutilizationandstoragestrainengineeringthroughadaptivelaboratoryevolutionandmicrobiomeoptimization