Early detection of left ventricular dysfunction in patients with end-stage renal disease on hemodialysis by speckle-tracking echocardiography

Background: In individuals with end-stage renal disease (ESRD) cardiovascular imaging modalities show a high prevalence of left ventricular hypertrophy (LVH), systolic/diastolic dysfunction and ventricular dilatation (dilated cardiomyopathy), which are strongly linked to a poor prognosis. Aim: The a...

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Main Authors: Saud Mohamed, Abdelaziz O. Mohamed, Mohamed G. Alsaady, Hala A. Mahmoud
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2025-01-01
Series:Heart India
Subjects:
Online Access:https://journals.lww.com/10.4103/heartindia.heartindia_66_24
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author Saud Mohamed
Abdelaziz O. Mohamed
Mohamed G. Alsaady
Hala A. Mahmoud
author_facet Saud Mohamed
Abdelaziz O. Mohamed
Mohamed G. Alsaady
Hala A. Mahmoud
author_sort Saud Mohamed
collection DOAJ
description Background: In individuals with end-stage renal disease (ESRD) cardiovascular imaging modalities show a high prevalence of left ventricular hypertrophy (LVH), systolic/diastolic dysfunction and ventricular dilatation (dilated cardiomyopathy), which are strongly linked to a poor prognosis. Aim: The aim of the present study was the early detection of left ventricle dysfunction in ESRD patients on hemodialysis (HD) using speckle-tracking imaging. Subjects and Methods: This was a cross-sectional study performed on 199 patients with ESRD that referred to HD unit in Aswan University Hospital. All patients underwent echocardiographic evaluation by traditional transthoracic 2D echocardiography, tissue Doppler imaging, and speckle tracking. Results: Global longitudinal strain was significantly lower in diabetic ESRD patients and in ESRD patients with LVH than nondiabetics and those without LVH (P < 0.05). Conclusion: Speckle-tracking echocardiography can early detect the left ventricle dysfunction in ESRD patients on HD, and global longitudinal strain is the most sensitive echocardiographic parameter to predict systolic dysfunction.
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spelling doaj-art-55e19e8748a244e59e3c7733a75c52f92025-08-20T02:16:19ZengWolters Kluwer Medknow PublicationsHeart India2321-449X2321-66382025-01-01131323810.4103/heartindia.heartindia_66_24Early detection of left ventricular dysfunction in patients with end-stage renal disease on hemodialysis by speckle-tracking echocardiographySaud MohamedAbdelaziz O. MohamedMohamed G. AlsaadyHala A. MahmoudBackground: In individuals with end-stage renal disease (ESRD) cardiovascular imaging modalities show a high prevalence of left ventricular hypertrophy (LVH), systolic/diastolic dysfunction and ventricular dilatation (dilated cardiomyopathy), which are strongly linked to a poor prognosis. Aim: The aim of the present study was the early detection of left ventricle dysfunction in ESRD patients on hemodialysis (HD) using speckle-tracking imaging. Subjects and Methods: This was a cross-sectional study performed on 199 patients with ESRD that referred to HD unit in Aswan University Hospital. All patients underwent echocardiographic evaluation by traditional transthoracic 2D echocardiography, tissue Doppler imaging, and speckle tracking. Results: Global longitudinal strain was significantly lower in diabetic ESRD patients and in ESRD patients with LVH than nondiabetics and those without LVH (P < 0.05). Conclusion: Speckle-tracking echocardiography can early detect the left ventricle dysfunction in ESRD patients on HD, and global longitudinal strain is the most sensitive echocardiographic parameter to predict systolic dysfunction.https://journals.lww.com/10.4103/heartindia.heartindia_66_24end-stage renal diseaseglshemodialysisleft ventricle dysfunctionspeckle-tracking imaging
spellingShingle Saud Mohamed
Abdelaziz O. Mohamed
Mohamed G. Alsaady
Hala A. Mahmoud
Early detection of left ventricular dysfunction in patients with end-stage renal disease on hemodialysis by speckle-tracking echocardiography
Heart India
end-stage renal disease
gls
hemodialysis
left ventricle dysfunction
speckle-tracking imaging
title Early detection of left ventricular dysfunction in patients with end-stage renal disease on hemodialysis by speckle-tracking echocardiography
title_full Early detection of left ventricular dysfunction in patients with end-stage renal disease on hemodialysis by speckle-tracking echocardiography
title_fullStr Early detection of left ventricular dysfunction in patients with end-stage renal disease on hemodialysis by speckle-tracking echocardiography
title_full_unstemmed Early detection of left ventricular dysfunction in patients with end-stage renal disease on hemodialysis by speckle-tracking echocardiography
title_short Early detection of left ventricular dysfunction in patients with end-stage renal disease on hemodialysis by speckle-tracking echocardiography
title_sort early detection of left ventricular dysfunction in patients with end stage renal disease on hemodialysis by speckle tracking echocardiography
topic end-stage renal disease
gls
hemodialysis
left ventricle dysfunction
speckle-tracking imaging
url https://journals.lww.com/10.4103/heartindia.heartindia_66_24
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AT abdelazizomohamed earlydetectionofleftventriculardysfunctioninpatientswithendstagerenaldiseaseonhemodialysisbyspeckletrackingechocardiography
AT mohamedgalsaady earlydetectionofleftventriculardysfunctioninpatientswithendstagerenaldiseaseonhemodialysisbyspeckletrackingechocardiography
AT halaamahmoud earlydetectionofleftventriculardysfunctioninpatientswithendstagerenaldiseaseonhemodialysisbyspeckletrackingechocardiography