Feasibility, Safety, and Efficacy of Segmental Spinal Anesthesia with Predominantly Isobaric Levobupivacaine: A Tertiary Care Hospital Study

Objective: To assess feasibility, safety, and efficacy of segmental spinal anesthesia with isobaric levobupivacaine in patients undergoing various abdominal and lower limb surgeries. Methods: This was a prospective cohort study conducted at the Department of Anesthesiology and Critical Care of Kot...

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Main Authors: Lalit Goyal, Saloni Gupta, Sachin Nagar, Vinay Bhargava
Format: Article
Language:English
Published: Universitas Padjadjaran 2024-09-01
Series:International Journal of Integrated Health Sciences
Subjects:
Online Access:https://journal.fk.unpad.ac.id/index.php/ijihs/article/view/3988
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author Lalit Goyal
Saloni Gupta
Sachin Nagar
Vinay Bhargava
author_facet Lalit Goyal
Saloni Gupta
Sachin Nagar
Vinay Bhargava
author_sort Lalit Goyal
collection DOAJ
description Objective: To assess feasibility, safety, and efficacy of segmental spinal anesthesia with isobaric levobupivacaine in patients undergoing various abdominal and lower limb surgeries. Methods: This was a prospective cohort study conducted at the Department of Anesthesiology and Critical Care of Kota Heart Institute and group of hospitals in India. The study involved  100 patients undergoing various abdominal and lower limb surgeries under segmental spinal anesthesia (SSA). Isobaric levobupivacaine 0.5% with fentanyl 20-25 μg or dexmedetomidine 5-10 as adjuvant or  hypobaric levobupivacaine 0.167%  was injected in intervertebral space depending on the surgery. Hemodynamic parameters, postoperative pain level, and adverse effects were analyzed with a p-value less than 0.05 was considered statistically significant. Results: An overall male predominance was observed with a 1:0.515 male-to-female ratio. The most affected age group was 41-50 years (37%), with a mean age of 44.51 ± 11.72 years. ASA classification indicated 34% of patients in ASA I, 40% in ASA II, 24% ASA III and 2% in ASA IV . The primary surgery was laparoscopic cholecystectomy (26%) in normal risk group and orthopedic in high-risk group(20%). Postoperative pain assessment showed mean VAS scores ranging from 1.92 to 3.42 at different time intervals. Common adverse effects were hemodynamic instability (13%), shoulder tip pain (33%), PONV (3%), headache (6%), pruritis (2%) and urinary retention (1%). The hemodynamic instability showed less incidence in ASA III/IV category. Conclusion: Segmental spinal anesthesia can be used successfully for abdominal and lower limb orthopedic surgeries in patients of ASA I to ASA IV.
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spelling doaj-art-55dcbf52366c4ffc8ec62e015c78fb952025-08-20T02:33:07ZengUniversitas PadjadjaranInternational Journal of Integrated Health Sciences2302-13812338-45062024-09-01122879410.15850/ijihs.v12.n2.39881765Feasibility, Safety, and Efficacy of Segmental Spinal Anesthesia with Predominantly Isobaric Levobupivacaine: A Tertiary Care Hospital StudyLalit Goyal0Saloni Gupta1Sachin Nagar2Vinay Bhargava3Anaesthesia and Critical care, Kota Heart Institute and General HospitalAnaesthesia and Critical care, Kota Heart Institute and General HospitalDepartment of Anaesthesia, Critical Care & Pain, Aarvy Healthcare Super Speciality Hospital, Kalyani Hospital GurugramAnaesthesia and Critical care, Kota Heart Institute and General HospitalObjective: To assess feasibility, safety, and efficacy of segmental spinal anesthesia with isobaric levobupivacaine in patients undergoing various abdominal and lower limb surgeries. Methods: This was a prospective cohort study conducted at the Department of Anesthesiology and Critical Care of Kota Heart Institute and group of hospitals in India. The study involved  100 patients undergoing various abdominal and lower limb surgeries under segmental spinal anesthesia (SSA). Isobaric levobupivacaine 0.5% with fentanyl 20-25 μg or dexmedetomidine 5-10 as adjuvant or  hypobaric levobupivacaine 0.167%  was injected in intervertebral space depending on the surgery. Hemodynamic parameters, postoperative pain level, and adverse effects were analyzed with a p-value less than 0.05 was considered statistically significant. Results: An overall male predominance was observed with a 1:0.515 male-to-female ratio. The most affected age group was 41-50 years (37%), with a mean age of 44.51 ± 11.72 years. ASA classification indicated 34% of patients in ASA I, 40% in ASA II, 24% ASA III and 2% in ASA IV . The primary surgery was laparoscopic cholecystectomy (26%) in normal risk group and orthopedic in high-risk group(20%). Postoperative pain assessment showed mean VAS scores ranging from 1.92 to 3.42 at different time intervals. Common adverse effects were hemodynamic instability (13%), shoulder tip pain (33%), PONV (3%), headache (6%), pruritis (2%) and urinary retention (1%). The hemodynamic instability showed less incidence in ASA III/IV category. Conclusion: Segmental spinal anesthesia can be used successfully for abdominal and lower limb orthopedic surgeries in patients of ASA I to ASA IV.https://journal.fk.unpad.ac.id/index.php/ijihs/article/view/3988asa grade, levobupivacaine, segmental spinal anesthesia, visual analogue scale
spellingShingle Lalit Goyal
Saloni Gupta
Sachin Nagar
Vinay Bhargava
Feasibility, Safety, and Efficacy of Segmental Spinal Anesthesia with Predominantly Isobaric Levobupivacaine: A Tertiary Care Hospital Study
International Journal of Integrated Health Sciences
asa grade, levobupivacaine, segmental spinal anesthesia, visual analogue scale
title Feasibility, Safety, and Efficacy of Segmental Spinal Anesthesia with Predominantly Isobaric Levobupivacaine: A Tertiary Care Hospital Study
title_full Feasibility, Safety, and Efficacy of Segmental Spinal Anesthesia with Predominantly Isobaric Levobupivacaine: A Tertiary Care Hospital Study
title_fullStr Feasibility, Safety, and Efficacy of Segmental Spinal Anesthesia with Predominantly Isobaric Levobupivacaine: A Tertiary Care Hospital Study
title_full_unstemmed Feasibility, Safety, and Efficacy of Segmental Spinal Anesthesia with Predominantly Isobaric Levobupivacaine: A Tertiary Care Hospital Study
title_short Feasibility, Safety, and Efficacy of Segmental Spinal Anesthesia with Predominantly Isobaric Levobupivacaine: A Tertiary Care Hospital Study
title_sort feasibility safety and efficacy of segmental spinal anesthesia with predominantly isobaric levobupivacaine a tertiary care hospital study
topic asa grade, levobupivacaine, segmental spinal anesthesia, visual analogue scale
url https://journal.fk.unpad.ac.id/index.php/ijihs/article/view/3988
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AT sachinnagar feasibilitysafetyandefficacyofsegmentalspinalanesthesiawithpredominantlyisobariclevobupivacaineatertiarycarehospitalstudy
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