Microbiome-mediated colonization resistance to carbapenem-resistant Klebsiella pneumoniae in ICU patients

Microbiome-mediated colonization resistance to carbapenem-resistant Klebsiella pneumoniae in ICU patients

Abstract Carbapenem-resistant Klebsiella pneumoniae (CRKP) causes serious intensive care unit (ICU)-acquired infections, yet the mechanisms of microbiota-mediated colonization resistance remain unclear. We analyzed the gut microbiome and metabolic profiles of healthy individuals and ICU patients, di...

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Bibliographic Details
Main Authors: Jing Yang, Yi Zhou, Aiping Du, Zhongwei Zhang, Bo Wang, Yongming Tian, Huan Liu, Lin Cai, Fang Pang, Yumei Li, Chunhua Du, Xijun Wu, Cong Yan, Wei Wu, Min Jiang, Ke Shen, Chi Zhang, Yu Feng, Yan Kang, Bairong Shen, Zhiyong Zong
Format: Article
Language:English
Published: Nature Portfolio 2025-08-01
Series:npj Biofilms and Microbiomes
Online Access:https://doi.org/10.1038/s41522-025-00791-x
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