Effects of community-acquired pneumonia on biventricular cardiac functions in children

Abstract Background This study aimed to evaluate the effects of community-acquired pneumonia (CAP) on cardiac function in children and compare the effectiveness of tissue Doppler imaging (TDI) and two-dimensional speckle tracking echocardiography (2D-STE) with conventional echocardiography in the ea...

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Main Authors: Rehab Elmeazawy, Esraa Abd Al-Fattah Sorour, Al Shimaa Badreldeen
Format: Article
Language:English
Published: BMC 2025-04-01
Series:Italian Journal of Pediatrics
Subjects:
Online Access:https://doi.org/10.1186/s13052-025-01965-1
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author Rehab Elmeazawy
Esraa Abd Al-Fattah Sorour
Al Shimaa Badreldeen
author_facet Rehab Elmeazawy
Esraa Abd Al-Fattah Sorour
Al Shimaa Badreldeen
author_sort Rehab Elmeazawy
collection DOAJ
description Abstract Background This study aimed to evaluate the effects of community-acquired pneumonia (CAP) on cardiac function in children and compare the effectiveness of tissue Doppler imaging (TDI) and two-dimensional speckle tracking echocardiography (2D-STE) with conventional echocardiography in the early detection of biventricular cardiac dysfunction in children with CAP. Methods The study included 50 hospitalized children diagnosed with CAP and 50 matched healthy controls. All patients underwent cardiac evaluation including conventional echocardiography, TDI, and 2D-STE. Results Fifty children with CAP with a mean age of 5.02 ± 2.46 years participated in the study. Thirty-two were male (64.0%). LV systolic function (S) and RV diastolic function (E′/A′) were significantly lower in the diseased group compared to the control group (p < 0.001). The myocardial performance index (MPI) of both ventricles was significantly higher in the diseased group compared to the control group (p < 0.001). In patients with CAP, the mean value of two-dimensional longitudinal strain (2D LS) was significantly lower than that of the control group (p < 0.001). No statistically significant differences in echocardiographic parameters were observed when comparing complicated and non-complicated CAP subgroups. Conclusion TDI and 2D-STE demonstrated the ability to detect early biventricular dysfunction in pediatric patients diagnosed with CAP.
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spelling doaj-art-55c5bba4a067487ca0535fd6753d3bf42025-08-20T03:18:41ZengBMCItalian Journal of Pediatrics1824-72882025-04-015111910.1186/s13052-025-01965-1Effects of community-acquired pneumonia on biventricular cardiac functions in childrenRehab Elmeazawy0Esraa Abd Al-Fattah Sorour1Al Shimaa Badreldeen2Department of Pediatrics, Faculty of Medicine, Tanta UniversityDepartment of Pediatrics, Faculty of Medicine, Tanta UniversityDepartment of Pediatrics, Faculty of Medicine, Tanta UniversityAbstract Background This study aimed to evaluate the effects of community-acquired pneumonia (CAP) on cardiac function in children and compare the effectiveness of tissue Doppler imaging (TDI) and two-dimensional speckle tracking echocardiography (2D-STE) with conventional echocardiography in the early detection of biventricular cardiac dysfunction in children with CAP. Methods The study included 50 hospitalized children diagnosed with CAP and 50 matched healthy controls. All patients underwent cardiac evaluation including conventional echocardiography, TDI, and 2D-STE. Results Fifty children with CAP with a mean age of 5.02 ± 2.46 years participated in the study. Thirty-two were male (64.0%). LV systolic function (S) and RV diastolic function (E′/A′) were significantly lower in the diseased group compared to the control group (p < 0.001). The myocardial performance index (MPI) of both ventricles was significantly higher in the diseased group compared to the control group (p < 0.001). In patients with CAP, the mean value of two-dimensional longitudinal strain (2D LS) was significantly lower than that of the control group (p < 0.001). No statistically significant differences in echocardiographic parameters were observed when comparing complicated and non-complicated CAP subgroups. Conclusion TDI and 2D-STE demonstrated the ability to detect early biventricular dysfunction in pediatric patients diagnosed with CAP.https://doi.org/10.1186/s13052-025-01965-1ChildrenPneumoniaSpeckle tracking echocardiographyTissue doppler imaging
spellingShingle Rehab Elmeazawy
Esraa Abd Al-Fattah Sorour
Al Shimaa Badreldeen
Effects of community-acquired pneumonia on biventricular cardiac functions in children
Italian Journal of Pediatrics
Children
Pneumonia
Speckle tracking echocardiography
Tissue doppler imaging
title Effects of community-acquired pneumonia on biventricular cardiac functions in children
title_full Effects of community-acquired pneumonia on biventricular cardiac functions in children
title_fullStr Effects of community-acquired pneumonia on biventricular cardiac functions in children
title_full_unstemmed Effects of community-acquired pneumonia on biventricular cardiac functions in children
title_short Effects of community-acquired pneumonia on biventricular cardiac functions in children
title_sort effects of community acquired pneumonia on biventricular cardiac functions in children
topic Children
Pneumonia
Speckle tracking echocardiography
Tissue doppler imaging
url https://doi.org/10.1186/s13052-025-01965-1
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AT esraaabdalfattahsorour effectsofcommunityacquiredpneumoniaonbiventricularcardiacfunctionsinchildren
AT alshimaabadreldeen effectsofcommunityacquiredpneumoniaonbiventricularcardiacfunctionsinchildren