Progress of sacubitril valsartan in researches on chronic kidney disease with diabetes and cardiovascular disease
Chronic kidney disease(CKD)and cardiovascular disease(CVD) are the major causes of death in patients with diabetes.The activation of renin-angiotensin-aldosterone system(RAAS) and natriuretic peptide(NP) system has attracted more and more attention in recent years.A dual-acting drug that simultaneou...
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| Format: | Article |
| Language: | zho |
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Editorial Department of Journal of Clinical Nephrology
2020-01-01
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| Series: | Linchuang shenzangbing zazhi |
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| Online Access: | http://www.lcszb.com/thesisDetails?columnId=57907280&Fpath=home&index=0 |
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| author | YANG Hui-juan CHEN Wei-dong PAN Yan |
| author_facet | YANG Hui-juan CHEN Wei-dong PAN Yan |
| author_sort | YANG Hui-juan |
| collection | DOAJ |
| description | Chronic kidney disease(CKD)and cardiovascular disease(CVD) are the major causes of death in patients with diabetes.The activation of renin-angiotensin-aldosterone system(RAAS) and natriuretic peptide(NP) system has attracted more and more attention in recent years.A dual-acting drug that simultaneously inhibits enkephalinase and renin-angiotensin has been developed.The first representative drug is Sacubitril Valsartan Sodium Tablet.It can delay the progression of heart failure and renal failure in patients,and can be a better choice for patients with diabetes complicated by CKD and CVD patients.Therefore,this study explores the relationship of RAAS and NP systems with CKD and CVD,and the protective effect of sacubitril valsartan on CKD and CVD with diabetes. |
| format | Article |
| id | doaj-art-55c470f8b81142b9a3a3db576e7637b6 |
| institution | OA Journals |
| issn | 1671-2390 |
| language | zho |
| publishDate | 2020-01-01 |
| publisher | Editorial Department of Journal of Clinical Nephrology |
| record_format | Article |
| series | Linchuang shenzangbing zazhi |
| spelling | doaj-art-55c470f8b81142b9a3a3db576e7637b62025-08-20T02:28:46ZzhoEditorial Department of Journal of Clinical NephrologyLinchuang shenzangbing zazhi1671-23902020-01-0160260557907280Progress of sacubitril valsartan in researches on chronic kidney disease with diabetes and cardiovascular diseaseYANG Hui-juanCHEN Wei-dongPAN YanChronic kidney disease(CKD)and cardiovascular disease(CVD) are the major causes of death in patients with diabetes.The activation of renin-angiotensin-aldosterone system(RAAS) and natriuretic peptide(NP) system has attracted more and more attention in recent years.A dual-acting drug that simultaneously inhibits enkephalinase and renin-angiotensin has been developed.The first representative drug is Sacubitril Valsartan Sodium Tablet.It can delay the progression of heart failure and renal failure in patients,and can be a better choice for patients with diabetes complicated by CKD and CVD patients.Therefore,this study explores the relationship of RAAS and NP systems with CKD and CVD,and the protective effect of sacubitril valsartan on CKD and CVD with diabetes.http://www.lcszb.com/thesisDetails?columnId=57907280&Fpath=home&index=0Sacubitril valsartanChronic kidney diseaseCardiovascular diseaseRenin-angiotensin-aldosterone systemNatriuretic peptide |
| spellingShingle | YANG Hui-juan CHEN Wei-dong PAN Yan Progress of sacubitril valsartan in researches on chronic kidney disease with diabetes and cardiovascular disease Linchuang shenzangbing zazhi Sacubitril valsartan Chronic kidney disease Cardiovascular disease Renin-angiotensin-aldosterone system Natriuretic peptide |
| title | Progress of sacubitril valsartan in researches on chronic kidney disease with diabetes and cardiovascular disease |
| title_full | Progress of sacubitril valsartan in researches on chronic kidney disease with diabetes and cardiovascular disease |
| title_fullStr | Progress of sacubitril valsartan in researches on chronic kidney disease with diabetes and cardiovascular disease |
| title_full_unstemmed | Progress of sacubitril valsartan in researches on chronic kidney disease with diabetes and cardiovascular disease |
| title_short | Progress of sacubitril valsartan in researches on chronic kidney disease with diabetes and cardiovascular disease |
| title_sort | progress of sacubitril valsartan in researches on chronic kidney disease with diabetes and cardiovascular disease |
| topic | Sacubitril valsartan Chronic kidney disease Cardiovascular disease Renin-angiotensin-aldosterone system Natriuretic peptide |
| url | http://www.lcszb.com/thesisDetails?columnId=57907280&Fpath=home&index=0 |
| work_keys_str_mv | AT yanghuijuan progressofsacubitrilvalsartaninresearchesonchronickidneydiseasewithdiabetesandcardiovasculardisease AT chenweidong progressofsacubitrilvalsartaninresearchesonchronickidneydiseasewithdiabetesandcardiovasculardisease AT panyan progressofsacubitrilvalsartaninresearchesonchronickidneydiseasewithdiabetesandcardiovasculardisease |