Long-term consumption of highland barley tea promotes healthy aging of skeletal muscle
Highland barley tea (HBT) is made from roasted barley seeds and is abundant in β-glucan, amino acids, minerals, phenolics, and other natural active ingredients. These natural compounds found in whole grains have been shown to slow aging and positively affect skeletal muscle function. As a result, st...
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| Format: | Article |
| Language: | English |
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Tsinghua University Press
2025-05-01
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| Series: | Food Science and Human Wellness |
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| Online Access: | https://www.sciopen.com/article/10.26599/FSHW.2024.9250108 |
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| author | Li Yan Chenzhipeng Nie Qingwei Zheng Mingcong Fan Waleed AL-Ansi Haifeng Qian Li Wang |
| author_facet | Li Yan Chenzhipeng Nie Qingwei Zheng Mingcong Fan Waleed AL-Ansi Haifeng Qian Li Wang |
| author_sort | Li Yan |
| collection | DOAJ |
| description | Highland barley tea (HBT) is made from roasted barley seeds and is abundant in β-glucan, amino acids, minerals, phenolics, and other natural active ingredients. These natural compounds found in whole grains have been shown to slow aging and positively affect skeletal muscle function. As a result, studying the effects of HBT on the skeletal muscle health of the elderly population is critical from a scientific and societal standpoint for improving their health status and reducing the medical burden on society. The antioxidant activity and the content of natural active substances were used as indicators to screen the optimal process of HBT brewing. The effects of long-term HBT consumption on aging in mice were investigated by using HBT as a substitute for drinking water in naturally aging mice for a 5-month intervention. Afterward, various factors were measured, such as basic physiological indices, inflammation, plasma metabolites, skeletal muscle function, and exercise capacity, to evaluate the effects of HBT on aging in mice. Long-term consumption of HBT reduced body and spleen weight, increased body weight percentage of skeletal muscle, and reduced plasma inflammation levels in aging mice. Metabolomic results showed increased plasma levels of the mitochondrial marker short-chain acylcarnitine and some amino acids. Additionally, there was a decrease in bile and long-chain acylcarnitine. The level of fibrosis in the gastrocnemius muscle of aging mice was suppressed, and the percentage of type Ⅰ muscle fibers was increased, improving the endurance of the mice. Thus, long-term consumption of HBT may reduce body weight and increase skeletal muscle mitochondrial activity and exercise capacity in aging mice by reducing inflammation levels and alleviating mitochondrial damage. |
| format | Article |
| id | doaj-art-55bcc6a96bd94ee09ce0aefa660d6d21 |
| institution | Kabale University |
| issn | 2097-0765 2213-4530 |
| language | English |
| publishDate | 2025-05-01 |
| publisher | Tsinghua University Press |
| record_format | Article |
| series | Food Science and Human Wellness |
| spelling | doaj-art-55bcc6a96bd94ee09ce0aefa660d6d212025-08-20T03:48:14ZengTsinghua University PressFood Science and Human Wellness2097-07652213-45302025-05-01145925010810.26599/FSHW.2024.9250108Long-term consumption of highland barley tea promotes healthy aging of skeletal muscleLi Yan0Chenzhipeng Nie1Qingwei Zheng2Mingcong Fan3Waleed AL-Ansi4Haifeng Qian5Li Wang6State Key Laboratory of Food Science and Technology, School of Food Science and Technology, Jiangnan University, Wuxi 214122, ChinaState Key Laboratory of Food Science and Technology, School of Food Science and Technology, Jiangnan University, Wuxi 214122, ChinaState Key Laboratory of Food Science and Technology, School of Food Science and Technology, Jiangnan University, Wuxi 214122, ChinaState Key Laboratory of Food Science and Technology, School of Food Science and Technology, Jiangnan University, Wuxi 214122, ChinaState Key Laboratory of Food Science and Technology, School of Food Science and Technology, Jiangnan University, Wuxi 214122, ChinaState Key Laboratory of Food Science and Technology, School of Food Science and Technology, Jiangnan University, Wuxi 214122, ChinaState Key Laboratory of Food Science and Technology, School of Food Science and Technology, Jiangnan University, Wuxi 214122, ChinaHighland barley tea (HBT) is made from roasted barley seeds and is abundant in β-glucan, amino acids, minerals, phenolics, and other natural active ingredients. These natural compounds found in whole grains have been shown to slow aging and positively affect skeletal muscle function. As a result, studying the effects of HBT on the skeletal muscle health of the elderly population is critical from a scientific and societal standpoint for improving their health status and reducing the medical burden on society. The antioxidant activity and the content of natural active substances were used as indicators to screen the optimal process of HBT brewing. The effects of long-term HBT consumption on aging in mice were investigated by using HBT as a substitute for drinking water in naturally aging mice for a 5-month intervention. Afterward, various factors were measured, such as basic physiological indices, inflammation, plasma metabolites, skeletal muscle function, and exercise capacity, to evaluate the effects of HBT on aging in mice. Long-term consumption of HBT reduced body and spleen weight, increased body weight percentage of skeletal muscle, and reduced plasma inflammation levels in aging mice. Metabolomic results showed increased plasma levels of the mitochondrial marker short-chain acylcarnitine and some amino acids. Additionally, there was a decrease in bile and long-chain acylcarnitine. The level of fibrosis in the gastrocnemius muscle of aging mice was suppressed, and the percentage of type Ⅰ muscle fibers was increased, improving the endurance of the mice. Thus, long-term consumption of HBT may reduce body weight and increase skeletal muscle mitochondrial activity and exercise capacity in aging mice by reducing inflammation levels and alleviating mitochondrial damage.https://www.sciopen.com/article/10.26599/FSHW.2024.9250108highland barleyskeletal muscleagingmitochondrial |
| spellingShingle | Li Yan Chenzhipeng Nie Qingwei Zheng Mingcong Fan Waleed AL-Ansi Haifeng Qian Li Wang Long-term consumption of highland barley tea promotes healthy aging of skeletal muscle Food Science and Human Wellness highland barley skeletal muscle aging mitochondrial |
| title | Long-term consumption of highland barley tea promotes healthy aging of skeletal muscle |
| title_full | Long-term consumption of highland barley tea promotes healthy aging of skeletal muscle |
| title_fullStr | Long-term consumption of highland barley tea promotes healthy aging of skeletal muscle |
| title_full_unstemmed | Long-term consumption of highland barley tea promotes healthy aging of skeletal muscle |
| title_short | Long-term consumption of highland barley tea promotes healthy aging of skeletal muscle |
| title_sort | long term consumption of highland barley tea promotes healthy aging of skeletal muscle |
| topic | highland barley skeletal muscle aging mitochondrial |
| url | https://www.sciopen.com/article/10.26599/FSHW.2024.9250108 |
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