Dose-sparing effects of novel adjuvants and aluminum hydroxide on two different vaccines in a neonatal mouse model

Dose-sparing effects of novel adjuvants and aluminum hydroxide on two different vaccines in a neonatal mouse model

Childhood vaccination provides protection against infectious diseases, but multiple vaccinations are required to achieve this. In situations like influenza epidemics or COVID-19 pandemic, vaccine demands may exceed production capacity, highlighting the need for dose-sparing strategies. Adjuvants can...

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Bibliographic Details
Main Authors: Jenny Lorena Molina Estupiñan, Poorya Foroutan Pajoohian, Gabriel Kristian Pedersen, Dennis Christensen, Serena Marchi, Emanuele Montomoli, Stefanía P. Bjarnarson, Ingileif Jonsdottir, Audur Anna Aradottir Pind
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-07-01
Series:Frontiers in Immunology
Subjects:
immunization
neonates
adjuvants
dose-sparing
antibodies
antibody-secreting cells
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1646677/full
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