A clinical case of parvovirus infection
This article shows current information about etiology, epidemiology and clinic of рarvovirus B19. Parvovirus infection is an acute infectious disease that is associated with a range of clinical conditions. The causative agent of the disease is parvovirus B19, which is tropic to the progenitor cells...
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| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | Russian |
| Published: |
Open Systems Publication
2021-06-01
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| Series: | Лечащий Врач |
| Subjects: | |
| Online Access: | https://journal.lvrach.ru/jour/article/view/218 |
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| Summary: | This article shows current information about etiology, epidemiology and clinic of рarvovirus B19. Parvovirus infection is an acute infectious disease that is associated with a range of clinical conditions. The causative agent of the disease is parvovirus B19, which is tropic to the progenitor cells of the red bone marrow. The most common mechanism of transmission is aerogenic, but there are also vertical and hemocontact mechanisms. Infection occurs by airborne, transplacental pathways, as well as by hemotransfusion. High-risk groups include people with congenital hematological diseases, immunosuppressive individuals, and pregnant women. Parvovirus infection during pregnancy is particularly dangerous. The virus causes blockage of fetal erythropoiesis, which leads to anemia, tissue hypoxia, noninflammatory dropsy, and fetal death. The most common symptoms of parvovirus infection are the development of infectious erythema, arthropathies, and transient aplastic anemia. Diagnostics of parvovirus infection includes isolation of the pathogen's DNA in the blood in the PCR reaction, as well as the use of the ELISA method with the detection of IgM and IgG in the acute period of the disease. Currently, etiotropic therapy and specific prevention of parvovirus infection are not available, and patients receive symptomatic therapy. The prognosis in most cases, is favorable. This article provides an overview of a clinical case of parvovirus infection in a patient admitted to the Infectious Diseases Clinical Hospital Two with complaints of fever and exanthema. |
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| ISSN: | 1560-5175 2687-1181 |