Optical coherence tomography in patients with somatotropin-producing pituitary adenoma

Optical coherence tomography (OCT) is widely used in ophthalmological practice. The review presents the results of OCT in patients with somatotropin-producing pituitary adenoma, or somatotropinoma, which is a hormone-active tumor of the adenohypophysis, characterized by excessive production of somat...

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Main Authors: N. A. Gavrilova, N. S. Gadzhieva, A. V. Kuz’mina
Format: Article
Language:Russian
Published: Real Time Ltd 2021-06-01
Series:Российский офтальмологический журнал
Subjects:
Online Access:https://roj.igb.ru/jour/article/view/664
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author N. A. Gavrilova
N. S. Gadzhieva
A. V. Kuz’mina
author_facet N. A. Gavrilova
N. S. Gadzhieva
A. V. Kuz’mina
author_sort N. A. Gavrilova
collection DOAJ
description Optical coherence tomography (OCT) is widely used in ophthalmological practice. The review presents the results of OCT in patients with somatotropin-producing pituitary adenoma, or somatotropinoma, which is a hormone-active tumor of the adenohypophysis, characterized by excessive production of somatotropic hormone (STH). It stimulates the secretion of type I insulin-like growth factor (IGF-I). The mechanisms of STH action (pro-angiogenic action, stimulation endothelial cell proliferation and migration, development of endothelial dysfunction and retinal edema) requires much attention to the results of examination of patients with somatotropinomas using modern diagnostic methods, such as OCT.
format Article
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institution Kabale University
issn 2072-0076
2587-5760
language Russian
publishDate 2021-06-01
publisher Real Time Ltd
record_format Article
series Российский офтальмологический журнал
spelling doaj-art-55a2b9a2595c491cae86b316cbf1ef7c2025-08-20T03:59:20ZrusReal Time LtdРоссийский офтальмологический журнал2072-00762587-57602021-06-01142818410.21516/2072-0076-2021-14-2-81-84360Optical coherence tomography in patients with somatotropin-producing pituitary adenomaN. A. Gavrilova0N. S. Gadzhieva1A. V. Kuz’mina2A.I. Evdokimov Moscow State Medical University of Medicine and DentistryA.I. Evdokimov Moscow State Medical University of Medicine and DentistryA.I. Evdokimov Moscow State Medical University of Medicine and DentistryOptical coherence tomography (OCT) is widely used in ophthalmological practice. The review presents the results of OCT in patients with somatotropin-producing pituitary adenoma, or somatotropinoma, which is a hormone-active tumor of the adenohypophysis, characterized by excessive production of somatotropic hormone (STH). It stimulates the secretion of type I insulin-like growth factor (IGF-I). The mechanisms of STH action (pro-angiogenic action, stimulation endothelial cell proliferation and migration, development of endothelial dysfunction and retinal edema) requires much attention to the results of examination of patients with somatotropinomas using modern diagnostic methods, such as OCT.https://roj.igb.ru/jour/article/view/664optical coherence tomographysomatotropinomadiagnostics
spellingShingle N. A. Gavrilova
N. S. Gadzhieva
A. V. Kuz’mina
Optical coherence tomography in patients with somatotropin-producing pituitary adenoma
Российский офтальмологический журнал
optical coherence tomography
somatotropinoma
diagnostics
title Optical coherence tomography in patients with somatotropin-producing pituitary adenoma
title_full Optical coherence tomography in patients with somatotropin-producing pituitary adenoma
title_fullStr Optical coherence tomography in patients with somatotropin-producing pituitary adenoma
title_full_unstemmed Optical coherence tomography in patients with somatotropin-producing pituitary adenoma
title_short Optical coherence tomography in patients with somatotropin-producing pituitary adenoma
title_sort optical coherence tomography in patients with somatotropin producing pituitary adenoma
topic optical coherence tomography
somatotropinoma
diagnostics
url https://roj.igb.ru/jour/article/view/664
work_keys_str_mv AT nagavrilova opticalcoherencetomographyinpatientswithsomatotropinproducingpituitaryadenoma
AT nsgadzhieva opticalcoherencetomographyinpatientswithsomatotropinproducingpituitaryadenoma
AT avkuzmina opticalcoherencetomographyinpatientswithsomatotropinproducingpituitaryadenoma