Synthesis and Evaluation of Some Coumarin Based Schiff's Bases as Potential Antimicrobial Agents'
A series of the title compounds 3-(4-(4, 5-dihydro-5-(substituted phenyl)-1H-3-pyrazolyl) phenylimino) methyl)-4-chloro-2H-chromen-2-one 5(a-g) have been synthesized. These compounds were characterized on the basis of their spectral (IR, 1H NMR) data and evaluated for antimicrobial activity in vitro...
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| Format: | Article |
| Language: | English |
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Wiley
2012-01-01
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| Series: | E-Journal of Chemistry |
| Online Access: | http://dx.doi.org/10.1155/2012/791091 |
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| _version_ | 1832559969234321408 |
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| author | Vishakha Bansode Meenakshi N. Deodhar |
| author_facet | Vishakha Bansode Meenakshi N. Deodhar |
| author_sort | Vishakha Bansode |
| collection | DOAJ |
| description | A series of the title compounds 3-(4-(4, 5-dihydro-5-(substituted phenyl)-1H-3-pyrazolyl) phenylimino) methyl)-4-chloro-2H-chromen-2-one 5(a-g) have been synthesized. These compounds were characterized on the basis of their spectral (IR, 1H NMR) data and evaluated for antimicrobial activity in vitro against gram positive bacteria, gram negative bacteria and fungi. The compound (5b) was found to be the most active with MIC of 20 µg/ml against all the tested organisms. |
| format | Article |
| id | doaj-art-559a6628180d4213814b4486a23a493e |
| institution | Kabale University |
| issn | 0973-4945 2090-9810 |
| language | English |
| publishDate | 2012-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | E-Journal of Chemistry |
| spelling | doaj-art-559a6628180d4213814b4486a23a493e2025-02-03T01:28:48ZengWileyE-Journal of Chemistry0973-49452090-98102012-01-01942079208810.1155/2012/791091Synthesis and Evaluation of Some Coumarin Based Schiff's Bases as Potential Antimicrobial Agents'Vishakha Bansode0Meenakshi N. Deodhar1Department of Pharmaceutical Chemistry, PDEA's Seth Govind Raghunath Sable College of Pharmacy, Saswad, Pune–412301, IndiaDepartment of Pharmaceutical Chemistry, PDEA's Seth Govind Raghunath Sable College of Pharmacy, Saswad, Pune–412301, IndiaA series of the title compounds 3-(4-(4, 5-dihydro-5-(substituted phenyl)-1H-3-pyrazolyl) phenylimino) methyl)-4-chloro-2H-chromen-2-one 5(a-g) have been synthesized. These compounds were characterized on the basis of their spectral (IR, 1H NMR) data and evaluated for antimicrobial activity in vitro against gram positive bacteria, gram negative bacteria and fungi. The compound (5b) was found to be the most active with MIC of 20 µg/ml against all the tested organisms.http://dx.doi.org/10.1155/2012/791091 |
| spellingShingle | Vishakha Bansode Meenakshi N. Deodhar Synthesis and Evaluation of Some Coumarin Based Schiff's Bases as Potential Antimicrobial Agents' E-Journal of Chemistry |
| title | Synthesis and Evaluation of Some Coumarin Based Schiff's Bases as Potential Antimicrobial Agents' |
| title_full | Synthesis and Evaluation of Some Coumarin Based Schiff's Bases as Potential Antimicrobial Agents' |
| title_fullStr | Synthesis and Evaluation of Some Coumarin Based Schiff's Bases as Potential Antimicrobial Agents' |
| title_full_unstemmed | Synthesis and Evaluation of Some Coumarin Based Schiff's Bases as Potential Antimicrobial Agents' |
| title_short | Synthesis and Evaluation of Some Coumarin Based Schiff's Bases as Potential Antimicrobial Agents' |
| title_sort | synthesis and evaluation of some coumarin based schiff s bases as potential antimicrobial agents |
| url | http://dx.doi.org/10.1155/2012/791091 |
| work_keys_str_mv | AT vishakhabansode synthesisandevaluationofsomecoumarinbasedschiffsbasesaspotentialantimicrobialagents AT meenakshindeodhar synthesisandevaluationofsomecoumarinbasedschiffsbasesaspotentialantimicrobialagents |