Human umbilical cord mesenchymal stem cells restore chemotherapy-induced premature ovarian failure by inhibiting ferroptosis in vitro ovarian culture system

Human umbilical cord mesenchymal stem cells restore chemotherapy-induced premature ovarian failure by inhibiting ferroptosis in vitro ovarian culture system

Abstract Background Mesenchymal stem cells (MSCs) have shown potential in repairing chemotherapy-induced premature ovarian failure (POF). However, challenges such as stem cell loss and immune phagocytosis post-transplantation hinder their application. Due to easy and safe handling, in vitro ovarian...

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Bibliographic Details
Main Authors: Jiaqi Chen, Zhuoying He, Wenjuan Xu, Yumiao Kang, Fengyu Zhu, Heng Tang, Jianye Wang, Fei Zhong
Format: Article
Language:English
Published: BMC 2024-11-01
Series:Reproductive Biology and Endocrinology
Subjects:
Umbilical cord mesenchymal stem cells
Premature ovarian failure
In vitro ovarian culture system
Ferroptosis
Fibrosis
Online Access:https://doi.org/10.1186/s12958-024-01310-x
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