Early intervention of baicalin suppresses obesity-induced adipose tissue fibrotic remodeling through Interfering NF-κB/HIF-1ɑ/GRK2 Signaling Pathway

Early intervention of baicalin suppresses obesity-induced adipose tissue fibrotic remodeling through Interfering NF-κB/HIF-1ɑ/GRK2 Signaling Pathway

Obesity-induced adipose tissue (AT) fibrosis is difficult to reverse, indicating the importance of early intervention. G protein-coupled receptor kinase 2 (GRK2) is a potential regulator of energy metabolism. Baicalin can improve insulin sensitivity and metabolic homeostasis. However, their impacts...

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Bibliographic Details
Main Authors: Ying Zeng, Wenting Li, Tingting Ma, Honglei Zhang, Jiaxing Xu, Kang Liu
Format: Article
Language:English
Published: Elsevier 2025-08-01
Series:Phytomedicine Plus
Subjects:
Baicalin
GRK2
Obesity
Adipose tissue fibrosis
NF-κB
HIF-1ɑ
Online Access:http://www.sciencedirect.com/science/article/pii/S2667031325000879
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