AICpred: Machine Learning-Based Prediction of Potential Anti-Inflammatory Compounds Targeting TLR4-MyD88 Binding Mechanism

AICpred: Machine Learning-Based Prediction of Potential Anti-Inflammatory Compounds Targeting TLR4-MyD88 Binding Mechanism

Toll-like receptor 4 (TLR4) has been implicated in the production of uncontrolled inflammation within the body, known as the cytokine storm. Studies that employ machine learning (ML) in the prediction of potential inhibitors of TLR4 are limited. This study introduces AICpred, a robust, free, user-fr...

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Bibliographic Details
Main Authors: Lucindah N. Fry-Nartey, Cyril Akafia, Ursula S. Nkonu, Spencer B. Baiden, Ignatus Nunana Dorvi, Kwasi Agyenkwa-Mawuli, Odame Agyapong, Claude Fiifi Hayford, Michael D. Wilson, Whelton A. Miller, Samuel K. Kwofie
Format: Article
Language:English
Published: MDPI AG 2025-01-01
Series:Information
Subjects:
toll-like receptor 4 (TLR4)
machine learning
anti-inflammatory
inflammatory
inhibitors
cytokine storm
Online Access:https://www.mdpi.com/2078-2489/16/1/34
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