Diabetic Heart Failure with Preserved Left Ventricular Ejection Fraction: Review of Current Pharmacotherapy
Diabetes is associated with several diabetic-related abnormalities which increase the risk of onset or worsening of heart failure. Recent studies showed that the majority of diabetic patients present with heart failure with preserved ejection fraction (HFpEF), and the prevalence of HFpEF in diabetic...
Saved in:
| Main Authors: | , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2022-01-01
|
| Series: | Journal of Diabetes Research |
| Online Access: | http://dx.doi.org/10.1155/2022/3366109 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1850226523979644928 |
|---|---|
| author | Jakub Benko Matej Samoš Tomáš Bolek Dana Prídavková Jakub Jurica Martin Jozef Péč Peter Galajda Marián Mokáň |
| author_facet | Jakub Benko Matej Samoš Tomáš Bolek Dana Prídavková Jakub Jurica Martin Jozef Péč Peter Galajda Marián Mokáň |
| author_sort | Jakub Benko |
| collection | DOAJ |
| description | Diabetes is associated with several diabetic-related abnormalities which increase the risk of onset or worsening of heart failure. Recent studies showed that the majority of diabetic patients present with heart failure with preserved ejection fraction (HFpEF), and the prevalence of HFpEF in diabetics is alarming. Moreover, outcomes in HFpEF are poor and could be compared to those of heart failure with reduced ejection fraction (HFrEF), with 1-year mortality ranging between 10 and 30%. In contrast to HFrEF, there is very limited evidence for pharmacologic therapy in symptomatic patients with preserved ejection fraction, and therefore, the optimal selection of treatment for diabetic HFpEF remains challenging. This narrative review article summarizes the currently available data on the pharmacological treatment of HFpEF in patients with diabetes. |
| format | Article |
| id | doaj-art-5573367a6d6f4ffd813b90803aaa1e2b |
| institution | OA Journals |
| issn | 2314-6753 |
| language | English |
| publishDate | 2022-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Journal of Diabetes Research |
| spelling | doaj-art-5573367a6d6f4ffd813b90803aaa1e2b2025-08-20T02:05:03ZengWileyJournal of Diabetes Research2314-67532022-01-01202210.1155/2022/3366109Diabetic Heart Failure with Preserved Left Ventricular Ejection Fraction: Review of Current PharmacotherapyJakub Benko0Matej Samoš1Tomáš Bolek2Dana Prídavková3Jakub Jurica4Martin Jozef Péč5Peter Galajda6Marián Mokáň7Department of Internal Medicine IDepartment of Internal Medicine IDepartment of Internal Medicine IDepartment of Internal Medicine IDepartment of Internal Medicine IDepartment of Internal Medicine IDepartment of Internal Medicine IDepartment of Internal Medicine IDiabetes is associated with several diabetic-related abnormalities which increase the risk of onset or worsening of heart failure. Recent studies showed that the majority of diabetic patients present with heart failure with preserved ejection fraction (HFpEF), and the prevalence of HFpEF in diabetics is alarming. Moreover, outcomes in HFpEF are poor and could be compared to those of heart failure with reduced ejection fraction (HFrEF), with 1-year mortality ranging between 10 and 30%. In contrast to HFrEF, there is very limited evidence for pharmacologic therapy in symptomatic patients with preserved ejection fraction, and therefore, the optimal selection of treatment for diabetic HFpEF remains challenging. This narrative review article summarizes the currently available data on the pharmacological treatment of HFpEF in patients with diabetes.http://dx.doi.org/10.1155/2022/3366109 |
| spellingShingle | Jakub Benko Matej Samoš Tomáš Bolek Dana Prídavková Jakub Jurica Martin Jozef Péč Peter Galajda Marián Mokáň Diabetic Heart Failure with Preserved Left Ventricular Ejection Fraction: Review of Current Pharmacotherapy Journal of Diabetes Research |
| title | Diabetic Heart Failure with Preserved Left Ventricular Ejection Fraction: Review of Current Pharmacotherapy |
| title_full | Diabetic Heart Failure with Preserved Left Ventricular Ejection Fraction: Review of Current Pharmacotherapy |
| title_fullStr | Diabetic Heart Failure with Preserved Left Ventricular Ejection Fraction: Review of Current Pharmacotherapy |
| title_full_unstemmed | Diabetic Heart Failure with Preserved Left Ventricular Ejection Fraction: Review of Current Pharmacotherapy |
| title_short | Diabetic Heart Failure with Preserved Left Ventricular Ejection Fraction: Review of Current Pharmacotherapy |
| title_sort | diabetic heart failure with preserved left ventricular ejection fraction review of current pharmacotherapy |
| url | http://dx.doi.org/10.1155/2022/3366109 |
| work_keys_str_mv | AT jakubbenko diabeticheartfailurewithpreservedleftventricularejectionfractionreviewofcurrentpharmacotherapy AT matejsamos diabeticheartfailurewithpreservedleftventricularejectionfractionreviewofcurrentpharmacotherapy AT tomasbolek diabeticheartfailurewithpreservedleftventricularejectionfractionreviewofcurrentpharmacotherapy AT danapridavkova diabeticheartfailurewithpreservedleftventricularejectionfractionreviewofcurrentpharmacotherapy AT jakubjurica diabeticheartfailurewithpreservedleftventricularejectionfractionreviewofcurrentpharmacotherapy AT martinjozefpec diabeticheartfailurewithpreservedleftventricularejectionfractionreviewofcurrentpharmacotherapy AT petergalajda diabeticheartfailurewithpreservedleftventricularejectionfractionreviewofcurrentpharmacotherapy AT marianmokan diabeticheartfailurewithpreservedleftventricularejectionfractionreviewofcurrentpharmacotherapy |