In vitro synergistic effect of AXL, FAK and ErbB receptors inhibitors for head and neck cancer

In vitro synergistic effect of AXL, FAK and ErbB receptors inhibitors for head and neck cancer

Abstract The prognosis for patients with head and neck cancer (HNC) is usually poor, highlighting the need for new therapeutic strategies. To this end, this study aims to evaluate the antitumor efficacy of a combined treatment with low doses of different molecular targeted drugs, i.e. Y15, a FAK inh...

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Main Authors: Valeria Lucarini, Valentina Angiolini, Daniela Nardozi, Monica Benvenuto, Chiara Focaccetti, Patrizia Mancini, Elena Splendiani, Tanja Milena Autilio, Claudio Cortese, Riccardo Bei, Gianluca Nicolai, Camilla Palumbo, Elisabetta Ferretti, Loredana Cifaldi, Roberto Bei, Laura Masuelli
Format: Article
Language:English
Published: BMC 2025-07-01
Series:Biology Direct
Online Access:https://doi.org/10.1186/s13062-025-00668-1
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