Sesquiterpenoid Hormones Farnesoic Acid and Methyl Farnesoate Regulate Different Gene Sets in Shrimp <i>Neocaridina davidi</i> Hepatopancreas
Sesquiterpenoid hormones such as the juvenile hormone and methyl farnesoate (MF) are well known to respectively control the development and reproduction in insects and crustaceans (such as shrimp, crabs, and lobsters). In recent years, the sesquiterpenoid hormone farnesoic acid (FA) has also been id...
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2025-06-01
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| author | Yehui Luan Wenyan Nong Wai Lok So Jerome Ho Lam Hui |
| author_facet | Yehui Luan Wenyan Nong Wai Lok So Jerome Ho Lam Hui |
| author_sort | Yehui Luan |
| collection | DOAJ |
| description | Sesquiterpenoid hormones such as the juvenile hormone and methyl farnesoate (MF) are well known to respectively control the development and reproduction in insects and crustaceans (such as shrimp, crabs, and lobsters). In recent years, the sesquiterpenoid hormone farnesoic acid (FA) has also been identified in other non-insect/crustacean invertebrates; despite this, their regulatory roles remain poorly understood. Here, we carried out the in vitro treatments of MF and FA on the hepatopancreas of female adult shrimps <i>Neocaridina davidi</i>. Transcriptomic analyses revealed a total of 65 and 112 differentially expressed genes in the MF- and FA-treated hepatopancreas at 3 h post-treatment, respectively. Gene pathway enrichment analyses further suggested that the two sesquiterpenoid hormones regulate different sets of genes, with the gene pathway involved in pancreatic secretion enriched only in the FA-treated hepatopancreas. This study demonstrates the differential regulatory roles between sesquiterpenoid forms, which warrants further investigation into the functions of FA in crustaceans. |
| format | Article |
| id | doaj-art-556028de2ee34ea0b12e557ab07c329c |
| institution | Kabale University |
| issn | 2218-273X |
| language | English |
| publishDate | 2025-06-01 |
| publisher | MDPI AG |
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| series | Biomolecules |
| spelling | doaj-art-556028de2ee34ea0b12e557ab07c329c2025-08-20T03:27:29ZengMDPI AGBiomolecules2218-273X2025-06-0115681510.3390/biom15060815Sesquiterpenoid Hormones Farnesoic Acid and Methyl Farnesoate Regulate Different Gene Sets in Shrimp <i>Neocaridina davidi</i> HepatopancreasYehui Luan0Wenyan Nong1Wai Lok So2Jerome Ho Lam Hui3School of Life Sciences, Simon F.S. Li Marine Science Laboratory, State Key Laboratory of Agrobiotechnology, Institute of Environment, Energy and Sustainability, The Chinese University of Hong Kong, Hong Kong SAR, ChinaSchool of Life Sciences, Simon F.S. Li Marine Science Laboratory, State Key Laboratory of Agrobiotechnology, Institute of Environment, Energy and Sustainability, The Chinese University of Hong Kong, Hong Kong SAR, ChinaSchool of Life Sciences, Simon F.S. Li Marine Science Laboratory, State Key Laboratory of Agrobiotechnology, Institute of Environment, Energy and Sustainability, The Chinese University of Hong Kong, Hong Kong SAR, ChinaSchool of Life Sciences, Simon F.S. Li Marine Science Laboratory, State Key Laboratory of Agrobiotechnology, Institute of Environment, Energy and Sustainability, The Chinese University of Hong Kong, Hong Kong SAR, ChinaSesquiterpenoid hormones such as the juvenile hormone and methyl farnesoate (MF) are well known to respectively control the development and reproduction in insects and crustaceans (such as shrimp, crabs, and lobsters). In recent years, the sesquiterpenoid hormone farnesoic acid (FA) has also been identified in other non-insect/crustacean invertebrates; despite this, their regulatory roles remain poorly understood. Here, we carried out the in vitro treatments of MF and FA on the hepatopancreas of female adult shrimps <i>Neocaridina davidi</i>. Transcriptomic analyses revealed a total of 65 and 112 differentially expressed genes in the MF- and FA-treated hepatopancreas at 3 h post-treatment, respectively. Gene pathway enrichment analyses further suggested that the two sesquiterpenoid hormones regulate different sets of genes, with the gene pathway involved in pancreatic secretion enriched only in the FA-treated hepatopancreas. This study demonstrates the differential regulatory roles between sesquiterpenoid forms, which warrants further investigation into the functions of FA in crustaceans.https://www.mdpi.com/2218-273X/15/6/815crustaceanshrimp<i>Neocaridina</i>genometranscriptomefarnesoic acid |
| spellingShingle | Yehui Luan Wenyan Nong Wai Lok So Jerome Ho Lam Hui Sesquiterpenoid Hormones Farnesoic Acid and Methyl Farnesoate Regulate Different Gene Sets in Shrimp <i>Neocaridina davidi</i> Hepatopancreas Biomolecules crustacean shrimp <i>Neocaridina</i> genome transcriptome farnesoic acid |
| title | Sesquiterpenoid Hormones Farnesoic Acid and Methyl Farnesoate Regulate Different Gene Sets in Shrimp <i>Neocaridina davidi</i> Hepatopancreas |
| title_full | Sesquiterpenoid Hormones Farnesoic Acid and Methyl Farnesoate Regulate Different Gene Sets in Shrimp <i>Neocaridina davidi</i> Hepatopancreas |
| title_fullStr | Sesquiterpenoid Hormones Farnesoic Acid and Methyl Farnesoate Regulate Different Gene Sets in Shrimp <i>Neocaridina davidi</i> Hepatopancreas |
| title_full_unstemmed | Sesquiterpenoid Hormones Farnesoic Acid and Methyl Farnesoate Regulate Different Gene Sets in Shrimp <i>Neocaridina davidi</i> Hepatopancreas |
| title_short | Sesquiterpenoid Hormones Farnesoic Acid and Methyl Farnesoate Regulate Different Gene Sets in Shrimp <i>Neocaridina davidi</i> Hepatopancreas |
| title_sort | sesquiterpenoid hormones farnesoic acid and methyl farnesoate regulate different gene sets in shrimp i neocaridina davidi i hepatopancreas |
| topic | crustacean shrimp <i>Neocaridina</i> genome transcriptome farnesoic acid |
| url | https://www.mdpi.com/2218-273X/15/6/815 |
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