Ribosylation-induced increase in advanced glycation end products has limited impacts on mechanical properties in human cortical bone

Ribosylation-induced increase in advanced glycation end products has limited impacts on mechanical properties in human cortical bone

Diabetes affects over 38 million individuals in the U.S. and is associated with a heightened risk of fractures despite normal or elevated bone mineral density (BMD). This increased fracture susceptibility may be linked to the accumulation of advanced glycation end products (AGEs), which are theorize...

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Bibliographic Details
Main Authors: Katelynn R. Gallagher, Olivia N. White, Andrew A. Tomaschke, Dyann M. Segvich, Joseph M. Wallace
Format: Article
Language:English
Published: Elsevier 2025-06-01
Series:Bone Reports
Subjects:
Diabetes
Microcomputed tomography
Dynamic mechanical analysis
Ribose/ribosylation
Fluorescence
Online Access:http://www.sciencedirect.com/science/article/pii/S235218722500018X
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