The Utility of Platelet Indices in Predicting Multiorgan Dysfunction in Scrub Typhus
Platelet indices have been used to diagnose and prognosticate infections such as tuberculosis, malaria, dengue, and septic shock. Platelet indices have previously not been used in the prediction of multiorgan dysfunction (MODS) in patients with scrub typhus. A three-year retrospective review of pati...
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| Format: | Article |
| Language: | English |
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Wiley
2020-01-01
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| Series: | Interdisciplinary Perspectives on Infectious Diseases |
| Online Access: | http://dx.doi.org/10.1155/2020/3870354 |
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| author | Saravanakumari Vijayakumar Stalin Viswanathan Dheeraj Jain |
| author_facet | Saravanakumari Vijayakumar Stalin Viswanathan Dheeraj Jain |
| author_sort | Saravanakumari Vijayakumar |
| collection | DOAJ |
| description | Platelet indices have been used to diagnose and prognosticate infections such as tuberculosis, malaria, dengue, and septic shock. Platelet indices have previously not been used in the prediction of multiorgan dysfunction (MODS) in patients with scrub typhus. A three-year retrospective review of patient charts was performed. Patients with and without MODS were compared. Platelet indices and other clinical and laboratory variables were used in logistic regression analysis to determine significant predictors. A ROC curve was generated with the platelet indices to predict MODS. Of 189 patients, 106 were male. Respiratory rate, serum creatinine, liver function tests, platelet count, thrombocytopenia <150 × 109/L, mean platelet volume (MPV) > 7.3 fL, and plateletcrit ≤0.19% varied significantly between patients with MODS and those without. Platelet indices are inexpensive and easily available. Only thrombocytopenia along with creatinine, alanine transaminase, and abnormal chest radiograph could significantly predict MODS in patients with scrub typhus. |
| format | Article |
| id | doaj-art-554ec4d5e33541b99d4e1a9afd598671 |
| institution | Kabale University |
| issn | 1687-708X 1687-7098 |
| language | English |
| publishDate | 2020-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Interdisciplinary Perspectives on Infectious Diseases |
| spelling | doaj-art-554ec4d5e33541b99d4e1a9afd5986712025-08-20T03:34:21ZengWileyInterdisciplinary Perspectives on Infectious Diseases1687-708X1687-70982020-01-01202010.1155/2020/38703543870354The Utility of Platelet Indices in Predicting Multiorgan Dysfunction in Scrub TyphusSaravanakumari Vijayakumar0Stalin Viswanathan1Dheeraj Jain2Department of Pathology, Sri Lakshmi Narayana Institute of Medical Sciences and Hospital, Kudapakkam Post, Pondicherry 605502, IndiaDepartment of General Medicine, JIPMER, Pondicherry 605009, IndiaDepartment of Medicine, Indira Gandhi Medical College and Research Institute, Kathirkamam, Pondicherry 605006, IndiaPlatelet indices have been used to diagnose and prognosticate infections such as tuberculosis, malaria, dengue, and septic shock. Platelet indices have previously not been used in the prediction of multiorgan dysfunction (MODS) in patients with scrub typhus. A three-year retrospective review of patient charts was performed. Patients with and without MODS were compared. Platelet indices and other clinical and laboratory variables were used in logistic regression analysis to determine significant predictors. A ROC curve was generated with the platelet indices to predict MODS. Of 189 patients, 106 were male. Respiratory rate, serum creatinine, liver function tests, platelet count, thrombocytopenia <150 × 109/L, mean platelet volume (MPV) > 7.3 fL, and plateletcrit ≤0.19% varied significantly between patients with MODS and those without. Platelet indices are inexpensive and easily available. Only thrombocytopenia along with creatinine, alanine transaminase, and abnormal chest radiograph could significantly predict MODS in patients with scrub typhus.http://dx.doi.org/10.1155/2020/3870354 |
| spellingShingle | Saravanakumari Vijayakumar Stalin Viswanathan Dheeraj Jain The Utility of Platelet Indices in Predicting Multiorgan Dysfunction in Scrub Typhus Interdisciplinary Perspectives on Infectious Diseases |
| title | The Utility of Platelet Indices in Predicting Multiorgan Dysfunction in Scrub Typhus |
| title_full | The Utility of Platelet Indices in Predicting Multiorgan Dysfunction in Scrub Typhus |
| title_fullStr | The Utility of Platelet Indices in Predicting Multiorgan Dysfunction in Scrub Typhus |
| title_full_unstemmed | The Utility of Platelet Indices in Predicting Multiorgan Dysfunction in Scrub Typhus |
| title_short | The Utility of Platelet Indices in Predicting Multiorgan Dysfunction in Scrub Typhus |
| title_sort | utility of platelet indices in predicting multiorgan dysfunction in scrub typhus |
| url | http://dx.doi.org/10.1155/2020/3870354 |
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