Coronary Artery Disease in Patients with Severe Mental Illness

Severe mental illnesses (SMI), such as schizophrenia and bipolar disorder, are associated with a decrease in life expectancy of up to two decades compared with the general population, with cardiovascular disease as the leading cause of death. SMI is associated with increased cardiovascular risk prof...

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Main Authors: Brian Tam To, Roman Roy, Narbeh Melikian, Fiona P Gaughran, Kevin O’Gallagher
Format: Article
Language:English
Published: Radcliffe Medical Media 2023-04-01
Series:Interventional Cardiology: Reviews, Research, Resources
Online Access:https://www.icrjournal.com/articleindex/icr.2022.31
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author Brian Tam To
Roman Roy
Narbeh Melikian
Fiona P Gaughran
Kevin O’Gallagher
author_facet Brian Tam To
Roman Roy
Narbeh Melikian
Fiona P Gaughran
Kevin O’Gallagher
author_sort Brian Tam To
collection DOAJ
description Severe mental illnesses (SMI), such as schizophrenia and bipolar disorder, are associated with a decrease in life expectancy of up to two decades compared with the general population, with cardiovascular disease as the leading cause of death. SMI is associated with increased cardiovascular risk profile and early onset of incident cardiovascular disease. Following an acute coronary syndrome, patients with SMI have a worse prognosis, but are less likely to receive invasive treatment. In this narrative review, the management of coronary artery disease in patients with SMI is discussed, and avenues for future research are highlighted.
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publishDate 2023-04-01
publisher Radcliffe Medical Media
record_format Article
series Interventional Cardiology: Reviews, Research, Resources
spelling doaj-art-554e05b0f22e4b5daf222a4d6c8114a32025-08-20T01:56:34ZengRadcliffe Medical MediaInterventional Cardiology: Reviews, Research, Resources1756-14771756-14852023-04-011810.15420/icr.2022.31Coronary Artery Disease in Patients with Severe Mental IllnessBrian Tam To0Roman Roy1Narbeh Melikian2Fiona P Gaughran3Kevin O’Gallagher4Cardiovascular Department, King’s College Hospital NHS Foundation Trust, London, UKCardiovascular Department, King’s College Hospital NHS Foundation Trust, London, UKCardiovascular Department, King’s College Hospital NHS Foundation Trust, London, UK; School of Cardiovascular and Metabolic Medicine & Sciences, British Heart Foundation Centre of Research Excellence, King’s College London, London, UK;Department of Psychosis Studies, Institute of Psychiatry, Psychology and Neuroscience, King’s College London, London, UK; National Psychosis Service, South London and Maudsley NHS Foundation Trust, London, UKCardiovascular Department, King’s College Hospital NHS Foundation Trust, London, UK; School of Cardiovascular and Metabolic Medicine & Sciences, British Heart Foundation Centre of Research Excellence, King’s College London, London, UK;Severe mental illnesses (SMI), such as schizophrenia and bipolar disorder, are associated with a decrease in life expectancy of up to two decades compared with the general population, with cardiovascular disease as the leading cause of death. SMI is associated with increased cardiovascular risk profile and early onset of incident cardiovascular disease. Following an acute coronary syndrome, patients with SMI have a worse prognosis, but are less likely to receive invasive treatment. In this narrative review, the management of coronary artery disease in patients with SMI is discussed, and avenues for future research are highlighted.https://www.icrjournal.com/articleindex/icr.2022.31
spellingShingle Brian Tam To
Roman Roy
Narbeh Melikian
Fiona P Gaughran
Kevin O’Gallagher
Coronary Artery Disease in Patients with Severe Mental Illness
Interventional Cardiology: Reviews, Research, Resources
title Coronary Artery Disease in Patients with Severe Mental Illness
title_full Coronary Artery Disease in Patients with Severe Mental Illness
title_fullStr Coronary Artery Disease in Patients with Severe Mental Illness
title_full_unstemmed Coronary Artery Disease in Patients with Severe Mental Illness
title_short Coronary Artery Disease in Patients with Severe Mental Illness
title_sort coronary artery disease in patients with severe mental illness
url https://www.icrjournal.com/articleindex/icr.2022.31
work_keys_str_mv AT briantamto coronaryarterydiseaseinpatientswithseverementalillness
AT romanroy coronaryarterydiseaseinpatientswithseverementalillness
AT narbehmelikian coronaryarterydiseaseinpatientswithseverementalillness
AT fionapgaughran coronaryarterydiseaseinpatientswithseverementalillness
AT kevinogallagher coronaryarterydiseaseinpatientswithseverementalillness