Subclinical Hepatic Encephalopathy in Cirrhotic Patients: Prevalence and Relationship to Liver Function
Neuropsychological tests were administered to 22 alcoholic cirrhotic patients, 20 nonalcoholic cirrhotic patients and 42 control subjects matched for age and educational background. Liver function estimated by Pugh score was identical in alcoholic and nonalcoholic cirrhotics. Thirty-two cirrhotic pa...
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| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
1991-01-01
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| Series: | Canadian Journal of Gastroenterology |
| Online Access: | http://dx.doi.org/10.1155/1991/680528 |
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| author | Gilles Pomier-Layrargues Ngoc Huu Nguyen Claire Faucher Jean-François Giguère Roger F Butterworth |
| author_facet | Gilles Pomier-Layrargues Ngoc Huu Nguyen Claire Faucher Jean-François Giguère Roger F Butterworth |
| author_sort | Gilles Pomier-Layrargues |
| collection | DOAJ |
| description | Neuropsychological tests were administered to 22 alcoholic cirrhotic patients, 20 nonalcoholic cirrhotic patients and 42 control subjects matched for age and educational background. Liver function estimated by Pugh score was identical in alcoholic and nonalcoholic cirrhotics. Thirty-two cirrhotic patients (76%) failed one or more psycho logical test. Performance was worse in cirrhotics than in controls in all but one test: the degree of neurological impairment was similar in alcoholics and nonalcoholics and correlation with the severity of Liver dysfunction was only marginal. A combination of the five more sensitive tests was able to identify 31 of 32 cirrhotic patients with subclinical encephalopathy; this ‘mini battery’ of tests can be performed within 10 mins. Suhclinical hepatic encephalopathy is frequent in cirrhotic patients and can adversely affect their psychosocial behaviour. |
| format | Article |
| id | doaj-art-554c518816ab47bdafbe4f55b806ca64 |
| institution | OA Journals |
| issn | 0835-7900 |
| language | English |
| publishDate | 1991-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Canadian Journal of Gastroenterology |
| spelling | doaj-art-554c518816ab47bdafbe4f55b806ca642025-08-20T02:05:06ZengWileyCanadian Journal of Gastroenterology0835-79001991-01-015412112510.1155/1991/680528Subclinical Hepatic Encephalopathy in Cirrhotic Patients: Prevalence and Relationship to Liver FunctionGilles Pomier-Layrargues0Ngoc Huu Nguyen1Claire Faucher2Jean-François Giguère3Roger F Butterworth4Liver Unit, Psychology Unit and Laboratory of Neurochemistry, Saint-Luc Hospital and André-Viallet Clinical Research Centre, University of Montreal, Montreal, Quebec, CanadaLiver Unit, Psychology Unit and Laboratory of Neurochemistry, Saint-Luc Hospital and André-Viallet Clinical Research Centre, University of Montreal, Montreal, Quebec, CanadaLiver Unit, Psychology Unit and Laboratory of Neurochemistry, Saint-Luc Hospital and André-Viallet Clinical Research Centre, University of Montreal, Montreal, Quebec, CanadaLiver Unit, Psychology Unit and Laboratory of Neurochemistry, Saint-Luc Hospital and André-Viallet Clinical Research Centre, University of Montreal, Montreal, Quebec, CanadaLiver Unit, Psychology Unit and Laboratory of Neurochemistry, Saint-Luc Hospital and André-Viallet Clinical Research Centre, University of Montreal, Montreal, Quebec, CanadaNeuropsychological tests were administered to 22 alcoholic cirrhotic patients, 20 nonalcoholic cirrhotic patients and 42 control subjects matched for age and educational background. Liver function estimated by Pugh score was identical in alcoholic and nonalcoholic cirrhotics. Thirty-two cirrhotic patients (76%) failed one or more psycho logical test. Performance was worse in cirrhotics than in controls in all but one test: the degree of neurological impairment was similar in alcoholics and nonalcoholics and correlation with the severity of Liver dysfunction was only marginal. A combination of the five more sensitive tests was able to identify 31 of 32 cirrhotic patients with subclinical encephalopathy; this ‘mini battery’ of tests can be performed within 10 mins. Suhclinical hepatic encephalopathy is frequent in cirrhotic patients and can adversely affect their psychosocial behaviour.http://dx.doi.org/10.1155/1991/680528 |
| spellingShingle | Gilles Pomier-Layrargues Ngoc Huu Nguyen Claire Faucher Jean-François Giguère Roger F Butterworth Subclinical Hepatic Encephalopathy in Cirrhotic Patients: Prevalence and Relationship to Liver Function Canadian Journal of Gastroenterology |
| title | Subclinical Hepatic Encephalopathy in Cirrhotic Patients: Prevalence and Relationship to Liver Function |
| title_full | Subclinical Hepatic Encephalopathy in Cirrhotic Patients: Prevalence and Relationship to Liver Function |
| title_fullStr | Subclinical Hepatic Encephalopathy in Cirrhotic Patients: Prevalence and Relationship to Liver Function |
| title_full_unstemmed | Subclinical Hepatic Encephalopathy in Cirrhotic Patients: Prevalence and Relationship to Liver Function |
| title_short | Subclinical Hepatic Encephalopathy in Cirrhotic Patients: Prevalence and Relationship to Liver Function |
| title_sort | subclinical hepatic encephalopathy in cirrhotic patients prevalence and relationship to liver function |
| url | http://dx.doi.org/10.1155/1991/680528 |
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