TERT Promoter C228T and C250T Hotspot Mutations Are Absent in BRAF V600E‐Positive Langerhans Cell Histiocytosis

TERT Promoter C228T and C250T Hotspot Mutations Are Absent in BRAF V600E‐Positive Langerhans Cell Histiocytosis

ABSTRACT Background In various malignancies, the co‐occurrence of BRAF V600E and TERT promoter mutations (C228T and C250T) has been associated with tumor aggressiveness and poor prognosis. However, the presence of these TERT promoter mutations in Langerhans cell histiocytosis (LCH) remains unexplore...

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Bibliographic Details
Main Authors: Abdou Malik Da Silva, Zofia Hélias‐Rodzewicz, Irena Ungureanu, Jean‐François Emile
Format: Article
Language:English
Published: Wiley 2025-08-01
Series:Cancer Medicine
Subjects:
BRAF
C228T mutation
C250T mutation
Langerhans cell histiocytosis
TERT
Online Access:https://doi.org/10.1002/cam4.71115
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