Vaccine antigen-based genotyping of Bordetella pertussis by direct Sanger sequencing of clinical samples in Peru from 2018 to 2019

Vaccine antigen-based genotyping of Bordetella pertussis by direct Sanger sequencing of clinical samples in Peru from 2018 to 2019

ABSTRACT Despite widespread vaccination, pertussis (caused by Bordetella pertussis) persists in many countries, frequently causing outbreaks and severe cases in infants. The resurgence of pertussis may be due to genetic changes in the vaccine antigens of circulating B. pertussis strains. However, cu...

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Bibliographic Details
Main Authors: Eduardo Juscamayta-López, Betsabé Vega-Abad, Faviola Valdivia, María Pía Soto, Helen Horna, Ruth García-de-la-Guarda
Format: Article
Language:English
Published: American Society for Microbiology 2025-06-01
Series:Microbiology Spectrum
Subjects:
Bordetella pertussis
pertussis
sequencing
vaccine antigen gene
allelic variant
genotype
Online Access:https://journals.asm.org/doi/10.1128/spectrum.02004-24
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