Cyclodextrin-Based Natural Deep Eutectic Solvents: Physicochemical Characterization and Application for Green Extraction of Polyphenols from <i>Moringa oleifera</i> Leaves
Natural deep eutectic solvents (NADESs) composed of citric acid and glucose or glycerol and glucose, both with and without the addition of β-cyclodextrin (BCD), were developed and characterized through physicochemical analysis. Parameters such as density, pH, water activity, refractive index, electr...
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2025-04-01
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| author | Melina Elizabeth Lionello Cristina Isabel dos Santos Ferreira María Florencia Mazzobre |
| author_facet | Melina Elizabeth Lionello Cristina Isabel dos Santos Ferreira María Florencia Mazzobre |
| author_sort | Melina Elizabeth Lionello |
| collection | DOAJ |
| description | Natural deep eutectic solvents (NADESs) composed of citric acid and glucose or glycerol and glucose, both with and without the addition of β-cyclodextrin (BCD), were developed and characterized through physicochemical analysis. Parameters such as density, pH, water activity, refractive index, electrical conductivity, and polarity were evaluated. Additionally, their thermal and rheological properties were assessed. The presence of BCD did not significantly affect the polarities of the NADESs but decreased the a<sub>w</sub> and increased the pH and the apparent viscosity. The designed NADESs were used to extract polyphenolic compounds from <i>Moringa oleifera</i> leaves, providing a sustainable alternative to conventional organic solvents. The results showed that NADESs achieved high extraction yields, demonstrating their effectiveness and potential applications in food and pharmaceutical industries. This study highlights the versatility of NADESs and their relevance in green chemistry and sustainable extraction technologies. |
| format | Article |
| id | doaj-art-552c336dd93841ed8f8dcbbc85db4785 |
| institution | Kabale University |
| issn | 2673-9976 |
| language | English |
| publishDate | 2025-04-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Biology and Life Sciences Forum |
| spelling | doaj-art-552c336dd93841ed8f8dcbbc85db47852025-08-20T03:26:15ZengMDPI AGBiology and Life Sciences Forum2673-99762025-04-014015310.3390/blsf2024040053Cyclodextrin-Based Natural Deep Eutectic Solvents: Physicochemical Characterization and Application for Green Extraction of Polyphenols from <i>Moringa oleifera</i> LeavesMelina Elizabeth Lionello0Cristina Isabel dos Santos Ferreira1María Florencia Mazzobre2CONICET–Universidad de Buenos Aires, Instituto de Tecnología de Alimentos y Procesos Químicos (ITAPROQ), Ciudad Universitaria, Buenos Aires C1428EGA, ArgentinaDepartamento de Química Orgánica, Facultad de Ciencias Exactas y Naturales, Universidad de Buenos Aires, Ciudad Universitaria, Buenos Aires C1428EGA, ArgentinaCONICET–Universidad de Buenos Aires, Instituto de Tecnología de Alimentos y Procesos Químicos (ITAPROQ), Ciudad Universitaria, Buenos Aires C1428EGA, ArgentinaNatural deep eutectic solvents (NADESs) composed of citric acid and glucose or glycerol and glucose, both with and without the addition of β-cyclodextrin (BCD), were developed and characterized through physicochemical analysis. Parameters such as density, pH, water activity, refractive index, electrical conductivity, and polarity were evaluated. Additionally, their thermal and rheological properties were assessed. The presence of BCD did not significantly affect the polarities of the NADESs but decreased the a<sub>w</sub> and increased the pH and the apparent viscosity. The designed NADESs were used to extract polyphenolic compounds from <i>Moringa oleifera</i> leaves, providing a sustainable alternative to conventional organic solvents. The results showed that NADESs achieved high extraction yields, demonstrating their effectiveness and potential applications in food and pharmaceutical industries. This study highlights the versatility of NADESs and their relevance in green chemistry and sustainable extraction technologies.https://www.mdpi.com/2673-9976/40/1/53NADESgreen extraction<i>M. oleifera</i>polyphenols |
| spellingShingle | Melina Elizabeth Lionello Cristina Isabel dos Santos Ferreira María Florencia Mazzobre Cyclodextrin-Based Natural Deep Eutectic Solvents: Physicochemical Characterization and Application for Green Extraction of Polyphenols from <i>Moringa oleifera</i> Leaves Biology and Life Sciences Forum NADES green extraction <i>M. oleifera</i> polyphenols |
| title | Cyclodextrin-Based Natural Deep Eutectic Solvents: Physicochemical Characterization and Application for Green Extraction of Polyphenols from <i>Moringa oleifera</i> Leaves |
| title_full | Cyclodextrin-Based Natural Deep Eutectic Solvents: Physicochemical Characterization and Application for Green Extraction of Polyphenols from <i>Moringa oleifera</i> Leaves |
| title_fullStr | Cyclodextrin-Based Natural Deep Eutectic Solvents: Physicochemical Characterization and Application for Green Extraction of Polyphenols from <i>Moringa oleifera</i> Leaves |
| title_full_unstemmed | Cyclodextrin-Based Natural Deep Eutectic Solvents: Physicochemical Characterization and Application for Green Extraction of Polyphenols from <i>Moringa oleifera</i> Leaves |
| title_short | Cyclodextrin-Based Natural Deep Eutectic Solvents: Physicochemical Characterization and Application for Green Extraction of Polyphenols from <i>Moringa oleifera</i> Leaves |
| title_sort | cyclodextrin based natural deep eutectic solvents physicochemical characterization and application for green extraction of polyphenols from i moringa oleifera i leaves |
| topic | NADES green extraction <i>M. oleifera</i> polyphenols |
| url | https://www.mdpi.com/2673-9976/40/1/53 |
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