Metformin Improves Epithelial-to-Mesenchymal Transition Induced by TGF-β1 in Renal Tubular Epithelial NRK-52E Cells via Inhibiting Egr-1

Metformin Improves Epithelial-to-Mesenchymal Transition Induced by TGF-β1 in Renal Tubular Epithelial NRK-52E Cells via Inhibiting Egr-1

The early growth response- (Egr-) 1 has been found to play a key role in organ fibrosis. Metformin has been shown to be effective in attenuating renal tubular epithelial-to-mesenchymal transition (EMT), which is involved in renal fibrosis. However, it is unknown whether metformin improves EMT via in...

Full description

Saved in:
Bibliographic Details
Main Authors: Meiping Guan, Wenqi Li, Lingling Xu, Yanmei Zeng, Dan Wang, Zongji Zheng, Fuping Lyv, Yaoming Xue
Format: Article
Language:English
Published: Wiley 2018-01-01
Series:Journal of Diabetes Research
Online Access:http://dx.doi.org/10.1155/2018/1031367
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items

Similar Items