Adoption Intentions Toward AI-based Clinical Decision Support Tools: A Tam Study on Hospital Pharmacists

The increasing prevalence of antibiotic resistance leads to an alarming challenge to global healthcare, necessitating the adoption of machine learning (ML)-driven clinical decision support systems (CDSS) to enhance antimicrobial stewardship. Despite its potential, hospital pharmacist’s adoption of...

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Main Authors: Muhammad Thesa Ghozali, Satibi, Gerhard Fortwengel
Format: Article
Language:English
Published: UUM Press 2025-07-01
Series:Journal of ICT
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Online Access:https://www.e-journal.uum.edu.my/index.php/jict/article/view/26905
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author Muhammad Thesa Ghozali
Satibi
Gerhard Fortwengel
author_facet Muhammad Thesa Ghozali
Satibi
Gerhard Fortwengel
author_sort Muhammad Thesa Ghozali
collection DOAJ
description The increasing prevalence of antibiotic resistance leads to an alarming challenge to global healthcare, necessitating the adoption of machine learning (ML)-driven clinical decision support systems (CDSS) to enhance antimicrobial stewardship. Despite its potential, hospital pharmacist’s adoption of ML-based antibiotic resistance predictors remains limited due to usability, trust, organisational support, and perceived risk concerns. This study uses an extended version of Technology Acceptance Model (TAM) to examine the primary factors influencing pharmacists’ behavioural intention (BI) to adopt the ML-driven CDSS. A cross-sectional survey was conducted among 235 hospital pharmacists across major provinces in Indonesia, using a PLS-SEM approach to test hypothesised relationships. The findings reveal that perceived usefulness (PU) (β = 0.355, p < 0.001) is the strongest predictor of BI, followed by trust in technology (TT) (β = 0.179, p = 0.017), social influence (SI) (β = 0.184, p = 0.009), and facilitating conditions (FC) (β = 0.150, p = 0.010). Perceived risk (PR) negatively affects BI (β = -0.103, p = 0.023), highlighting concerns over AI reliability. The study underlines the need for hospital administrators to enhance IT support and training, policymakers to establish AI regulatory frameworks, and professional organisations to promote AI acceptance through peer advocacy. Clinically, increased adoption of ML-driven CDSS can improve the accuracy of antibiotic prescribing, reduce resistance rates, and enhance patient safety. It provides insights into optimising AI interventions in antimicrobial stewardship programmes and guiding future implementation strategies in hospital pharmacy practice.
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spelling doaj-art-551f73afd96c40e48fe36398ce6eb01f2025-08-20T03:22:48ZengUUM PressJournal of ICT1675-414X2180-38622025-07-0124310.32890/jict2025.24.3.3Adoption Intentions Toward AI-based Clinical Decision Support Tools: A Tam Study on Hospital PharmacistsMuhammad Thesa Ghozali0Satibi1Gerhard Fortwengel2Department of Pharmaceutical Management, School of Pharmacy, Faculty of Medicine and Health Sciences, Universitas Muhammadiyah Yogyakarta, IndonesiaDepartment of Pharmaceutics, Faculty of Pharmacy, Universitas Gadjah Mada, IndonesiaFakultat III, Hochschule Hannover – University of Applied Sciences and Arts, Expo Plaza, Hannover, Lower Saxony, Germany The increasing prevalence of antibiotic resistance leads to an alarming challenge to global healthcare, necessitating the adoption of machine learning (ML)-driven clinical decision support systems (CDSS) to enhance antimicrobial stewardship. Despite its potential, hospital pharmacist’s adoption of ML-based antibiotic resistance predictors remains limited due to usability, trust, organisational support, and perceived risk concerns. This study uses an extended version of Technology Acceptance Model (TAM) to examine the primary factors influencing pharmacists’ behavioural intention (BI) to adopt the ML-driven CDSS. A cross-sectional survey was conducted among 235 hospital pharmacists across major provinces in Indonesia, using a PLS-SEM approach to test hypothesised relationships. The findings reveal that perceived usefulness (PU) (β = 0.355, p < 0.001) is the strongest predictor of BI, followed by trust in technology (TT) (β = 0.179, p = 0.017), social influence (SI) (β = 0.184, p = 0.009), and facilitating conditions (FC) (β = 0.150, p = 0.010). Perceived risk (PR) negatively affects BI (β = -0.103, p = 0.023), highlighting concerns over AI reliability. The study underlines the need for hospital administrators to enhance IT support and training, policymakers to establish AI regulatory frameworks, and professional organisations to promote AI acceptance through peer advocacy. Clinically, increased adoption of ML-driven CDSS can improve the accuracy of antibiotic prescribing, reduce resistance rates, and enhance patient safety. It provides insights into optimising AI interventions in antimicrobial stewardship programmes and guiding future implementation strategies in hospital pharmacy practice. https://www.e-journal.uum.edu.my/index.php/jict/article/view/26905Artificial intelligenceclinical decision support systemmachine learningpharmacist adoptiontechnology acceptance model
spellingShingle Muhammad Thesa Ghozali
Satibi
Gerhard Fortwengel
Adoption Intentions Toward AI-based Clinical Decision Support Tools: A Tam Study on Hospital Pharmacists
Journal of ICT
Artificial intelligence
clinical decision support system
machine learning
pharmacist adoption
technology acceptance model
title Adoption Intentions Toward AI-based Clinical Decision Support Tools: A Tam Study on Hospital Pharmacists
title_full Adoption Intentions Toward AI-based Clinical Decision Support Tools: A Tam Study on Hospital Pharmacists
title_fullStr Adoption Intentions Toward AI-based Clinical Decision Support Tools: A Tam Study on Hospital Pharmacists
title_full_unstemmed Adoption Intentions Toward AI-based Clinical Decision Support Tools: A Tam Study on Hospital Pharmacists
title_short Adoption Intentions Toward AI-based Clinical Decision Support Tools: A Tam Study on Hospital Pharmacists
title_sort adoption intentions toward ai based clinical decision support tools a tam study on hospital pharmacists
topic Artificial intelligence
clinical decision support system
machine learning
pharmacist adoption
technology acceptance model
url https://www.e-journal.uum.edu.my/index.php/jict/article/view/26905
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AT satibi adoptionintentionstowardaibasedclinicaldecisionsupporttoolsatamstudyonhospitalpharmacists
AT gerhardfortwengel adoptionintentionstowardaibasedclinicaldecisionsupporttoolsatamstudyonhospitalpharmacists