Non‐synaptic interictal epileptiform discharges propagating from CA3 to CA1 induce synaptic depression in the hippocampus

Non‐synaptic interictal epileptiform discharges propagating from CA3 to CA1 induce synaptic depression in the hippocampus

Abstract Objective Patients with epilepsy contend with memory impairment associated with the prevalence of interictal epileptiform discharges (IEDs). IEDs can propagate without synaptic transmission in both in vivo and in vitro rodent hippocampi. We focused our investigation on the effects of these...

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Bibliographic Details
Main Authors: Lauren H. Zukowski, Jiaxin Zhou, Snigdha Chawla, Chia‐Chu Chiang, Dominique M. Durand
Format: Article
Language:English
Published: Wiley 2025-08-01
Series:Epilepsia Open
Subjects:
IEDs
synaptic depression
DCS
non‐synaptic propagation
Online Access:https://doi.org/10.1002/epi4.70098
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