Hybrid immunity-based induction of durable pan-endemic-coronavirus immunity in the elderly

Summary: Repeated vaccinations and infections have led to diverse states of hybrid immunity against SARS-CoV-2 in the global population. However, age and comorbidities can compromise protection against severe disease, and antibody-mediated immunity is undercut by viral immune escape mutations. Wheth...

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Main Authors: Lucie Loyal, Julian Braun, Ulf Reimer, Lil Meyer-Arndt, Larissa Henze, Beate Kruse, Manuela Dingeldey, Maike Mangold, Janina Behrens, Pinkus Tober Lau, Janine Michel, Marica Grossegesse, Karsten Schnatbaum, Holger Wenschuh, Wibke Johannis, Veronica Di Cristanziano, Andreas Nitsche, Florian Klein, Leif-Erik Sander, Andreas Thiel
Format: Article
Language:English
Published: Elsevier 2025-02-01
Series:Cell Reports
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Online Access:http://www.sciencedirect.com/science/article/pii/S2211124725000853
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