Effects of children's microbiota on adipose and intestinal development in sex-matched mice persist into adulthood following a single fecal microbiota transplantation

Effects of children's microbiota on adipose and intestinal development in sex-matched mice persist into adulthood following a single fecal microbiota transplantation

Background: The global prevalence of obesity and type 2 diabetes, particularly among children, is rising, yet the long-term impacts of early-life fecal microbiota transplantation (FMT) on metabolic health remain poorly understood. Objectives: To investigate how early-life FMT from children to young,...

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Main Authors: Federica La Rosa, Maria Angela Guzzardi, Mercedes Pardo-Tendero, Monica Barone, Chiara Ruocco, Gabriele Conti, Daniele Panetta, Daria Riabitch, Silvia Bernardi, Assuero Giorgetti, Daniela Campani, Daniel Monleon, Enzo Nisoli, Patrizia Brigidi, Patricia Iozzo
Format: Article
Language:English
Published: Elsevier 2025-07-01
Series:Molecular Metabolism
Subjects:
Obesity
Type 2 diabetes
Positron emission tomography
Gut microbiota
Metabolomics
Adipose tissue
Online Access:http://www.sciencedirect.com/science/article/pii/S221287782500064X
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