Comprehensive Safety Exposure‐Response Analysis to Support Ritlecitinib Dose Selection

ABSTRACT Ritlecitinib is a kinase inhibitor drug recently approved for the treatment of alopecia areata (AA) in both adults and adolescents based on a single, combined Phase 2b/3 study. Various QD doses with and without a loading dose have been evaluated in the pivotal Phase 2b/3 study. Therefore, c...

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Bibliographic Details
Main Authors: Yeamin Huh, Ruolun Qiu, John Prybylski, Jessica Wojciechowski, Yuchen Wang, Vivek S. Purohit
Format: Article
Language:English
Published: Wiley 2025-06-01
Series:CPT: Pharmacometrics & Systems Pharmacology
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Online Access:https://doi.org/10.1002/psp4.70030
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