Toxoplasmosis and liver disease: literature review and clinical observation

Toxoplasmosis is a widespread ubiquatorial disease. A distinctive feature of this parasitosis is the predominance of latent forms. As a rule, in people with intact immune systems, the disease is asymptomatic. Severe cases of toxoplasmosis are usually associated with immunodeficiencies. At the same t...

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Main Authors: V. A. Greshnyakova, L. G. Gorjacheva
Format: Article
Language:Russian
Published: Journal Infectology 2021-07-01
Series:Журнал инфектологии
Subjects:
Online Access:https://journal.niidi.ru/jofin/article/view/1216
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author V. A. Greshnyakova
L. G. Gorjacheva
author_facet V. A. Greshnyakova
L. G. Gorjacheva
author_sort V. A. Greshnyakova
collection DOAJ
description Toxoplasmosis is a widespread ubiquatorial disease. A distinctive feature of this parasitosis is the predominance of latent forms. As a rule, in people with intact immune systems, the disease is asymptomatic. Severe cases of toxoplasmosis are usually associated with immunodeficiencies. At the same time, in cases of a manifest course in immunocompetent persons, toxoplasmosis is characterized by a polymorphism of clinical manifestations with damage to almost all organs and systems. In addition to the widely reported lesions of the eyes, brain, and intrauterine infection (IUI) associated with T. gondii, there are reports of damage to the liver, heart, lungs, and even multisystem cases of visceral toxoplasmosis. The article describes a clinical observation of toxoplasma hepatitis in a child with chronic viral hepatitis C. This clinical observation demonstrates the possibility of liver damage in the structure of toxoplasmosis and confirms the significance of this parasitosis among the population of patients with liver diseases.
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issn 2072-6732
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record_format Article
series Журнал инфектологии
spelling doaj-art-54f821ca6cc84c27bdbe7491cc9b980f2025-08-20T02:55:14ZrusJournal InfectologyЖурнал инфектологии2072-67322021-07-0113213514110.22625/2072-6732-2021-13-2-135-141918Toxoplasmosis and liver disease: literature review and clinical observationV. A. Greshnyakova0L. G. Gorjacheva1Pediatric Research and Clinical Center for Infectious DiseasesPediatric Research and Clinical Center for Infectious Diseases; Saint-Petersburg State Pediatric Medical UniversityToxoplasmosis is a widespread ubiquatorial disease. A distinctive feature of this parasitosis is the predominance of latent forms. As a rule, in people with intact immune systems, the disease is asymptomatic. Severe cases of toxoplasmosis are usually associated with immunodeficiencies. At the same time, in cases of a manifest course in immunocompetent persons, toxoplasmosis is characterized by a polymorphism of clinical manifestations with damage to almost all organs and systems. In addition to the widely reported lesions of the eyes, brain, and intrauterine infection (IUI) associated with T. gondii, there are reports of damage to the liver, heart, lungs, and even multisystem cases of visceral toxoplasmosis. The article describes a clinical observation of toxoplasma hepatitis in a child with chronic viral hepatitis C. This clinical observation demonstrates the possibility of liver damage in the structure of toxoplasmosis and confirms the significance of this parasitosis among the population of patients with liver diseases.https://journal.niidi.ru/jofin/article/view/1216toxoplasma hepatitisvisceral toxoplasmosistoxoplasmosistoxoplasmosis in childrenhepatitis ctoxoplasma gondii
spellingShingle V. A. Greshnyakova
L. G. Gorjacheva
Toxoplasmosis and liver disease: literature review and clinical observation
Журнал инфектологии
toxoplasma hepatitis
visceral toxoplasmosis
toxoplasmosis
toxoplasmosis in children
hepatitis c
toxoplasma gondii
title Toxoplasmosis and liver disease: literature review and clinical observation
title_full Toxoplasmosis and liver disease: literature review and clinical observation
title_fullStr Toxoplasmosis and liver disease: literature review and clinical observation
title_full_unstemmed Toxoplasmosis and liver disease: literature review and clinical observation
title_short Toxoplasmosis and liver disease: literature review and clinical observation
title_sort toxoplasmosis and liver disease literature review and clinical observation
topic toxoplasma hepatitis
visceral toxoplasmosis
toxoplasmosis
toxoplasmosis in children
hepatitis c
toxoplasma gondii
url https://journal.niidi.ru/jofin/article/view/1216
work_keys_str_mv AT vagreshnyakova toxoplasmosisandliverdiseaseliteraturereviewandclinicalobservation
AT lggorjacheva toxoplasmosisandliverdiseaseliteraturereviewandclinicalobservation