Sinus Bradycardia in an Adolescent Taking Lamotrigine

Lamotrigine is commonly prescribed for the treatment of neurological conditions and is increasingly being prescribed for psychiatric conditions as well. Although largely well tolerated, it is known to have a number of potential side effects, and in March 2021, the FDA issued its most recent warning...

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Main Authors: Genevieve Davis, Kristen Ward, Sarah Mohiuddin
Format: Article
Language:English
Published: Wiley 2022-01-01
Series:Case Reports in Psychiatry
Online Access:http://dx.doi.org/10.1155/2022/3353684
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author Genevieve Davis
Kristen Ward
Sarah Mohiuddin
author_facet Genevieve Davis
Kristen Ward
Sarah Mohiuddin
author_sort Genevieve Davis
collection DOAJ
description Lamotrigine is commonly prescribed for the treatment of neurological conditions and is increasingly being prescribed for psychiatric conditions as well. Although largely well tolerated, it is known to have a number of potential side effects, and in March 2021, the FDA issued its most recent warning for the medication due to its increased risk of cardiac arrhythmias. In this report, we describe a case in which an adolescent patient was found to be bradycardic after starting lamotrigine for antidepressant augmentation, with a gradual return to normal heart rate as the medication was subsequently tapered and discontinued. Further research is needed to more accurately estimate the risk of cardiac side effects and to establish appropriate monitoring guidelines for cardiac arrhythmias in those taking lamotrigine.
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institution Kabale University
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series Case Reports in Psychiatry
spelling doaj-art-54efa89d26634a43b0f322b75b3d5d3f2025-08-20T03:34:20ZengWileyCase Reports in Psychiatry2090-68382022-01-01202210.1155/2022/3353684Sinus Bradycardia in an Adolescent Taking LamotrigineGenevieve Davis0Kristen Ward1Sarah Mohiuddin2Department of PsychiatryDepartment of PsychiatryDepartment of PsychiatryLamotrigine is commonly prescribed for the treatment of neurological conditions and is increasingly being prescribed for psychiatric conditions as well. Although largely well tolerated, it is known to have a number of potential side effects, and in March 2021, the FDA issued its most recent warning for the medication due to its increased risk of cardiac arrhythmias. In this report, we describe a case in which an adolescent patient was found to be bradycardic after starting lamotrigine for antidepressant augmentation, with a gradual return to normal heart rate as the medication was subsequently tapered and discontinued. Further research is needed to more accurately estimate the risk of cardiac side effects and to establish appropriate monitoring guidelines for cardiac arrhythmias in those taking lamotrigine.http://dx.doi.org/10.1155/2022/3353684
spellingShingle Genevieve Davis
Kristen Ward
Sarah Mohiuddin
Sinus Bradycardia in an Adolescent Taking Lamotrigine
Case Reports in Psychiatry
title Sinus Bradycardia in an Adolescent Taking Lamotrigine
title_full Sinus Bradycardia in an Adolescent Taking Lamotrigine
title_fullStr Sinus Bradycardia in an Adolescent Taking Lamotrigine
title_full_unstemmed Sinus Bradycardia in an Adolescent Taking Lamotrigine
title_short Sinus Bradycardia in an Adolescent Taking Lamotrigine
title_sort sinus bradycardia in an adolescent taking lamotrigine
url http://dx.doi.org/10.1155/2022/3353684
work_keys_str_mv AT genevievedavis sinusbradycardiainanadolescenttakinglamotrigine
AT kristenward sinusbradycardiainanadolescenttakinglamotrigine
AT sarahmohiuddin sinusbradycardiainanadolescenttakinglamotrigine