Stroke-mimics in stroke-units. Evaluation after changes imposed by randomized trials
Abstract A larger therapeutic window for stroke treatment requires a significant change in the organization of emergency services, avoiding the increase in number of imaging exams and indirectly the time to treatment. Objective: To highlight the relation between faster clinical evaluation and stro...
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| Format: | Article |
| Language: | English |
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Thieme Revinter Publicações
2020-03-01
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| Series: | Arquivos de Neuro-Psiquiatria |
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| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2020000200088&tlng=en |
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| author | Héloïse IFERGAN Aymeric AMELOT Mohammad ISMAIL Marie GAUDRON Jean-Philippe COTTIER Ana Paula NARATA |
| author_facet | Héloïse IFERGAN Aymeric AMELOT Mohammad ISMAIL Marie GAUDRON Jean-Philippe COTTIER Ana Paula NARATA |
| author_sort | Héloïse IFERGAN |
| collection | DOAJ |
| description | Abstract A larger therapeutic window for stroke treatment requires a significant change in the organization of emergency services, avoiding the increase in number of imaging exams and indirectly the time to treatment. Objective: To highlight the relation between faster clinical evaluation and stroke over-suspicion and consequently excessive imaging acquisition. To identify predictors of ischemic stroke and stroke mimics (SM), aiming for better patient selection for comprehensive neuroimaging and reperfusion therapies. Methods: Retrospective, cohort, observational, single-center study that reviewed all consecutive files of patients presenting with acute neurological symptoms who underwent CT scan or MRI from July 1, 2016 to July 1, 2017. Results: 736 patient files were reviewed. 385 patients (52.3%) presented with confirmed acute ischemic infarct, 93 (12.6%) had another brain lesion mimicking acute ischemia, and 258 (35.1%) had normal imaging. Acute stroke was more frequent in elderly patients with atrial fibrillation, arterial hypertension, or dysarthria or right motor impairment. Stroke mimic was associated with female patients with low vascular risk factors, low NIHSS, and patients with decreased level of consciousness or symptoms suggestive of posterior circulation. Discussion: 47.7% of all patients seen at the stroke unit did not have acute stroke lesions. Clinical assessment data have been used to provide indicators of acute stroke and stroke mimic patients, and symptoms corresponding to acute stroke and stroke mimic seem to be similar in the literature. Conclusion: Considering that the number of patients admitted for stroke treatment will increase even further with a larger therapeutic window for mechanical thrombectomy and for thrombolysis, a diagnostic decision-making algorithm for stroke patients is required in order to reinforce the suspicion of stroke indicating an urgent MRI. |
| format | Article |
| id | doaj-art-54ea87f3e49a49beb9759c84ddd74ece |
| institution | Kabale University |
| issn | 1678-4227 |
| language | English |
| publishDate | 2020-03-01 |
| publisher | Thieme Revinter Publicações |
| record_format | Article |
| series | Arquivos de Neuro-Psiquiatria |
| spelling | doaj-art-54ea87f3e49a49beb9759c84ddd74ece2025-08-20T03:34:21ZengThieme Revinter PublicaçõesArquivos de Neuro-Psiquiatria1678-42272020-03-01782889510.1590/0004-282x20190154Stroke-mimics in stroke-units. Evaluation after changes imposed by randomized trialsHéloïse IFERGANAymeric AMELOThttps://orcid.org/0000-0003-3659-291XMohammad ISMAILhttps://orcid.org/0000-0002-1455-1482Marie GAUDRONJean-Philippe COTTIERhttps://orcid.org/0000-0003-0618-4026Ana Paula NARATAhttps://orcid.org/0000-0001-5658-1439Abstract A larger therapeutic window for stroke treatment requires a significant change in the organization of emergency services, avoiding the increase in number of imaging exams and indirectly the time to treatment. Objective: To highlight the relation between faster clinical evaluation and stroke over-suspicion and consequently excessive imaging acquisition. To identify predictors of ischemic stroke and stroke mimics (SM), aiming for better patient selection for comprehensive neuroimaging and reperfusion therapies. Methods: Retrospective, cohort, observational, single-center study that reviewed all consecutive files of patients presenting with acute neurological symptoms who underwent CT scan or MRI from July 1, 2016 to July 1, 2017. Results: 736 patient files were reviewed. 385 patients (52.3%) presented with confirmed acute ischemic infarct, 93 (12.6%) had another brain lesion mimicking acute ischemia, and 258 (35.1%) had normal imaging. Acute stroke was more frequent in elderly patients with atrial fibrillation, arterial hypertension, or dysarthria or right motor impairment. Stroke mimic was associated with female patients with low vascular risk factors, low NIHSS, and patients with decreased level of consciousness or symptoms suggestive of posterior circulation. Discussion: 47.7% of all patients seen at the stroke unit did not have acute stroke lesions. Clinical assessment data have been used to provide indicators of acute stroke and stroke mimic patients, and symptoms corresponding to acute stroke and stroke mimic seem to be similar in the literature. Conclusion: Considering that the number of patients admitted for stroke treatment will increase even further with a larger therapeutic window for mechanical thrombectomy and for thrombolysis, a diagnostic decision-making algorithm for stroke patients is required in order to reinforce the suspicion of stroke indicating an urgent MRI.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2020000200088&tlng=enstrokestroke mimicthrombectomythrombolysis |
| spellingShingle | Héloïse IFERGAN Aymeric AMELOT Mohammad ISMAIL Marie GAUDRON Jean-Philippe COTTIER Ana Paula NARATA Stroke-mimics in stroke-units. Evaluation after changes imposed by randomized trials Arquivos de Neuro-Psiquiatria stroke stroke mimic thrombectomy thrombolysis |
| title | Stroke-mimics in stroke-units. Evaluation after changes imposed by randomized trials |
| title_full | Stroke-mimics in stroke-units. Evaluation after changes imposed by randomized trials |
| title_fullStr | Stroke-mimics in stroke-units. Evaluation after changes imposed by randomized trials |
| title_full_unstemmed | Stroke-mimics in stroke-units. Evaluation after changes imposed by randomized trials |
| title_short | Stroke-mimics in stroke-units. Evaluation after changes imposed by randomized trials |
| title_sort | stroke mimics in stroke units evaluation after changes imposed by randomized trials |
| topic | stroke stroke mimic thrombectomy thrombolysis |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2020000200088&tlng=en |
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