Whole-body diffusion-weighted magnetic resonance imaging by estimating the measurable diffusion coefficient in Hodgkin lymphoma
Objective: to determine whether the measurable diffusion coefficient (MIC) may be used to differentiate normal and lymphomatosisaltered lymph nodes (LNs) in patients with Hodgkin lymphoma (HL).Material and methods. Whole-body magnetic resonance (MR) imaging was used to compare the MICs of LNs in 27...
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Luchevaya Diagnostika, LLC
2016-02-01
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| Series: | Вестник рентгенологии и радиологии |
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| Online Access: | https://www.russianradiology.ru/jour/article/view/15 |
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| author | A. I. Mikhaylov V. O. Panov I. E. Tyurin |
| author_facet | A. I. Mikhaylov V. O. Panov I. E. Tyurin |
| author_sort | A. I. Mikhaylov |
| collection | DOAJ |
| description | Objective: to determine whether the measurable diffusion coefficient (MIC) may be used to differentiate normal and lymphomatosisaltered lymph nodes (LNs) in patients with Hodgkin lymphoma (HL).Material and methods. Whole-body magnetic resonance (MR) imaging was used to compare the MICs of LNs in 27 apparently healthy individuals and 41 patients with a verified diagnosis of HL.Results. Construction of 95% confidence intervals showed that the MICs of normal LNs were in the range of 1.00 to 1.73× ×10-3 mm2/sec and significantly higher (p<0.05) than those of lymphomatosis-affected LNs (MIC, 0.59 to 0.94×10-3 mm2/sec). The cut-off point (for discretization) of normal and lymphomatosis-altered LNs was in the range of 0.94 to 1.00×10-3 mm2/sec. Consequently, the LN with a MIC of less than 0.94×10-3 mm2/sec may be thought of as affected by the lymphomatous process.Conclusion. MIC calculation permits differentiation of normal and affected LNs having equal signal characteristics (including those on diffusion-weighted MR images). |
| format | Article |
| id | doaj-art-54e6fd6638f643ff828b91f800787d93 |
| institution | DOAJ |
| issn | 0042-4676 2619-0478 |
| language | English |
| publishDate | 2016-02-01 |
| publisher | Luchevaya Diagnostika, LLC |
| record_format | Article |
| series | Вестник рентгенологии и радиологии |
| spelling | doaj-art-54e6fd6638f643ff828b91f800787d932025-08-20T03:18:02ZengLuchevaya Diagnostika, LLCВестник рентгенологии и радиологии0042-46762619-04782016-02-0102283410.20862/0042-4676-2015-0-2-28-3415Whole-body diffusion-weighted magnetic resonance imaging by estimating the measurable diffusion coefficient in Hodgkin lymphomaA. I. Mikhaylov0V. O. Panov1I. E. Tyurin2Russian Medical Academy of Postgraduate Education, Ministry of Health of the RFRussian Medical Academy of Postgraduate Education, Ministry of Health of the RFRussian Medical Academy of Postgraduate Education, Ministry of Health of the RFObjective: to determine whether the measurable diffusion coefficient (MIC) may be used to differentiate normal and lymphomatosisaltered lymph nodes (LNs) in patients with Hodgkin lymphoma (HL).Material and methods. Whole-body magnetic resonance (MR) imaging was used to compare the MICs of LNs in 27 apparently healthy individuals and 41 patients with a verified diagnosis of HL.Results. Construction of 95% confidence intervals showed that the MICs of normal LNs were in the range of 1.00 to 1.73× ×10-3 mm2/sec and significantly higher (p<0.05) than those of lymphomatosis-affected LNs (MIC, 0.59 to 0.94×10-3 mm2/sec). The cut-off point (for discretization) of normal and lymphomatosis-altered LNs was in the range of 0.94 to 1.00×10-3 mm2/sec. Consequently, the LN with a MIC of less than 0.94×10-3 mm2/sec may be thought of as affected by the lymphomatous process.Conclusion. MIC calculation permits differentiation of normal and affected LNs having equal signal characteristics (including those on diffusion-weighted MR images).https://www.russianradiology.ru/jour/article/view/15hodgkin lymphomawhole-body magnetic resonance imagingpositron emission tomographydiffusiondiffusion-weighted imagesmeasurable diffusion coefficient |
| spellingShingle | A. I. Mikhaylov V. O. Panov I. E. Tyurin Whole-body diffusion-weighted magnetic resonance imaging by estimating the measurable diffusion coefficient in Hodgkin lymphoma Вестник рентгенологии и радиологии hodgkin lymphoma whole-body magnetic resonance imaging positron emission tomography diffusion diffusion-weighted images measurable diffusion coefficient |
| title | Whole-body diffusion-weighted magnetic resonance imaging by estimating the measurable diffusion coefficient in Hodgkin lymphoma |
| title_full | Whole-body diffusion-weighted magnetic resonance imaging by estimating the measurable diffusion coefficient in Hodgkin lymphoma |
| title_fullStr | Whole-body diffusion-weighted magnetic resonance imaging by estimating the measurable diffusion coefficient in Hodgkin lymphoma |
| title_full_unstemmed | Whole-body diffusion-weighted magnetic resonance imaging by estimating the measurable diffusion coefficient in Hodgkin lymphoma |
| title_short | Whole-body diffusion-weighted magnetic resonance imaging by estimating the measurable diffusion coefficient in Hodgkin lymphoma |
| title_sort | whole body diffusion weighted magnetic resonance imaging by estimating the measurable diffusion coefficient in hodgkin lymphoma |
| topic | hodgkin lymphoma whole-body magnetic resonance imaging positron emission tomography diffusion diffusion-weighted images measurable diffusion coefficient |
| url | https://www.russianradiology.ru/jour/article/view/15 |
| work_keys_str_mv | AT aimikhaylov wholebodydiffusionweightedmagneticresonanceimagingbyestimatingthemeasurablediffusioncoefficientinhodgkinlymphoma AT vopanov wholebodydiffusionweightedmagneticresonanceimagingbyestimatingthemeasurablediffusioncoefficientinhodgkinlymphoma AT ietyurin wholebodydiffusionweightedmagneticresonanceimagingbyestimatingthemeasurablediffusioncoefficientinhodgkinlymphoma |