The role and mechanism of NAT10‐mediated ac4C modification in tumor development and progression

The role and mechanism of NAT10‐mediated ac4C modification in tumor development and progression

Abstract RNA modification has emerged as a crucial area of research in epigenetics, significantly influencing tumor biology by regulating RNA metabolism. N‐acetyltransferase 10 (NAT10)‐mediated N4‐acetylcytidine (ac4C) modification, the sole known acetylation in eukaryotic RNA, influences cancer pat...

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Main Authors: Zhuoran Gu, Libin Zou, Xinjian Pan, Yang Yu, Yongqiang Liu, Zhijin Zhang, Ji Liu, Shiyu Mao, Junfeng Zhang, Changcheng Guo, Wei Li, Jiang Geng, Wentao Zhang, Xudong Yao, Bing Shen
Format: Article
Language:English
Published: Wiley 2024-12-01
Series:MedComm
Subjects:
cancer
epitranscriptome
N4‐acetylation (ac4C)
N‐acetyltransferase 10 (NAT10)
RNA modification
Online Access:https://doi.org/10.1002/mco2.70026
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