Loperamide increases mouse gut transit time in a dose-dependent manner with treatment duration-dependent effects on distinct gut microbial taxa

Loperamide increases mouse gut transit time in a dose-dependent manner with treatment duration-dependent effects on distinct gut microbial taxa

Intestinal transit time has been recognized as an important factor in shaping the gut microbiota, although causality remains to be firmly demonstrated. The aim of this study was to evaluate the effect of different loperamide doses on the mouse intestinal transit time and to investigate the effects o...

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Bibliographic Details
Main Authors: Anna Pii Hjørne, Martin Steen Mortensen, Tine Rask Licht, Martin Frederik Laursen
Format: Article
Language:English
Published: Cambridge University Press 2025-01-01
Series:Gut Microbiome
Subjects:
gut microbiome
transit time
loperamide
Online Access:https://www.cambridge.org/core/product/identifier/S2632289725000052/type/journal_article
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