Hemophagocytic Lymphohistiocytosis and Disseminated Histoplasmosis in an HIV Patient
We present a case of a 54-year-old male, with newly detected HIV with low CD4 counts, diagnosed with hemophagocytic lymphohistiocytosis secondary to disseminated histoplasmosis. The history of his high-risk sexual behavior, fever, and pancytopenia led to clinical suspicion of HIV which was confirmed...
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| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Wolters Kluwer Medknow Publications
2025-06-01
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| Series: | Journal of Pharmacy and Bioallied Sciences |
| Subjects: | |
| Online Access: | https://journals.lww.com/10.4103/jpbs.jpbs_1735_24 |
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| Summary: | We present a case of a 54-year-old male, with newly detected HIV with low CD4 counts, diagnosed with hemophagocytic lymphohistiocytosis secondary to disseminated histoplasmosis. The history of his high-risk sexual behavior, fever, and pancytopenia led to clinical suspicion of HIV which was confirmed on serology. Hemophagocytosis was detected on bone marrow aspiration cytology and histoplasmosis was diagnosed on ultrasound-guided fine needle aspiration cytology of cervical lymph nodes. Timely interference of antiretroviral therapy (ART), antifungals, and identification of HLH lead to recovery of the patient. |
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| ISSN: | 0976-4879 0975-7406 |