The Impact of Obesity on Pain Perception During and After Subcutaneous Injections: A Cross-Sectional Analysis

(1) Background: The administration of subcutaneous (SC) injectables is among the most frequent procedures a nurse performs in daily practice. The needle for the injection must pass through the skin barrier to reach the SC space, where the drug will be deposited. This procedure can cause pain to the...

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Main Authors: Candelaria de la Merced Díaz-González, Josefa María Ramal-López, Milagros de la Rosa-Hormiga
Format: Article
Language:English
Published: MDPI AG 2024-11-01
Series:Obesities
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Online Access:https://www.mdpi.com/2673-4168/4/4/35
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Summary:(1) Background: The administration of subcutaneous (SC) injectables is among the most frequent procedures a nurse performs in daily practice. The needle for the injection must pass through the skin barrier to reach the SC space, where the drug will be deposited. This procedure can cause pain to the patient and local lesions. Local fat measurement can be performed by measuring the skin fold. Previous studies have found higher levels of pain in people with obesity receiving SC insulin, and this study thus aimed to measure pain levels <i>during</i> and <i>after</i> an SC injection of low-molecular-weight heparin (LMWH) and identify how age, gender, and obesity may modulate the level of pain <i>during</i> and <i>after</i> the procedure. (2) Methods: This was a cross-sectional study, and the variables included age, gender, body mass index (BMI), BMI quartile, abdominal skin folds (ASFs), ASF quartile, and pain level <i>during</i> and <i>after</i> injection. A caliper was used to measure ASFs, height and weight were used to calculate BMI, and the Visual Analog Scale (VAS) was used to measure pain. (3) Results: The sample amounted to 202 participants, which was not considered representative of the study population. The average age was 64.3 years, and females predominated (62.40%). Of these participants, 42.5% were obese, and 29.1% were overweight. The average pain levels were low <i>during</i> (1.4) and <i>after</i> injection (1.9), highlighting the absence of pain <i>during</i> injection in 29.7% and <i>after</i> injection in 34.2%. (4) Conclusions: Obesity was associated with increased pain, but when adjusted for age, the pain was no longer significant. Females and young participants showed a significant relationship with pain <i>during</i> injection. Age, gender, and obesity had a statistically significant relationship with pain level. Participants with obesity (according to BMI and ASF) showed the highest levels of pain <i>during</i> and <i>after</i> injection. <i>After</i> injection, there was an increase in pain in most cases, possibly due to the discomfort caused by the drug itself, an aspect considered in the drug’s technical data sheet as a frequent adverse effect (>1/10 to <1/100). However, the drug volume does not seem to be related to pain in this study.
ISSN:2673-4168