Cortical Diffusivity, a Biomarker for Early Neuronal Damage, Is Associated with Amyloid-β Deposition: A Pilot Study

Cortical Diffusivity, a Biomarker for Early Neuronal Damage, Is Associated with Amyloid-β Deposition: A Pilot Study

Pathological alterations in Alzheimer’s disease (AD) begin several years prior to symptom onset. Cortical mean diffusivity (cMD) may be used as a measure of early grey matter damage in AD as it reflects the breakdown of microstructural barriers preceding volumetric changes and affecting cognitive fu...

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Bibliographic Details
Main Authors: Justine Debatisse, Fangda Leng, Azhaar Ashraf, Paul Edison
Format: Article
Language:English
Published: MDPI AG 2025-01-01
Series:Cells
Subjects:
alzheimer’s disease
amyloid-β
cortical mean diffusivity
mild cognitive impairment
tau
Online Access:https://www.mdpi.com/2073-4409/14/3/155
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