Recent advances in organic fluorophore-based Schiff base metal complexes: Applications in biomedicine and related fields

Schiff bases are formed through the condensation of primary amines with aldehydes or ketones. Due to their simple synthesis and versatile properties, they are highly favored as ligands in coordination chemistry. They are widely applied in fields such as biology, industry, food packaging, dyes, polym...

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Main Authors: Mani Rajasekar, Jennita Mary, Meenamigai Sivakumar, Showparnickaa Subburao Ravichandran, Dharshini Srinivasan
Format: Article
Language:English
Published: Elsevier 2025-05-01
Series:Results in Chemistry
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Online Access:http://www.sciencedirect.com/science/article/pii/S2211715625001493
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author Mani Rajasekar
Jennita Mary
Meenamigai Sivakumar
Showparnickaa Subburao Ravichandran
Dharshini Srinivasan
author_facet Mani Rajasekar
Jennita Mary
Meenamigai Sivakumar
Showparnickaa Subburao Ravichandran
Dharshini Srinivasan
author_sort Mani Rajasekar
collection DOAJ
description Schiff bases are formed through the condensation of primary amines with aldehydes or ketones. Due to their simple synthesis and versatile properties, they are highly favored as ligands in coordination chemistry. They are widely applied in fields such as biology, industry, food packaging, dyes, polymers, and oxygen detectors. Schiff base ligands are crucial in forming transition metal complexes, which serve as precursors for synthesizing metal and metal chalcogenide nanoparticles. Organic Fluorophore Schiff bases containing fluorophore groups have gained attention for their enhanced photophysical properties and broad pharmacological activities. Their metal complexes are efficient in catalyzing organic oxidation reactions. The structural diversity and ability to chelate metals make these compounds highly adaptable for various applications. This review explores the preparation, physical, biological properties, and catalytic applications of Organic Fluorophore Schiff bases metal complexes for biomedical applications.
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institution Kabale University
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language English
publishDate 2025-05-01
publisher Elsevier
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series Results in Chemistry
spelling doaj-art-54a0709d853a43e69250d34e4c8138fc2025-08-20T03:46:49ZengElsevierResults in Chemistry2211-71562025-05-011510216610.1016/j.rechem.2025.102166Recent advances in organic fluorophore-based Schiff base metal complexes: Applications in biomedicine and related fieldsMani Rajasekar0Jennita Mary1Meenamigai Sivakumar2Showparnickaa Subburao Ravichandran3Dharshini Srinivasan4Centre for Molecular and Nanomedical Sciences, International Research Centre, Sathyabama Institute of Science and Technology (Deemed to be University), Chennai 600 119, Tamil Nadu, India; Corresponding author.Centre for Molecular and Nanomedical Sciences, International Research Centre, Sathyabama Institute of Science and Technology (Deemed to be University), Chennai 600 119, Tamil Nadu, India; School of Bio and Chemical Engineering, Department of Biotechnology, Sathyabama Institute of Science and Technology (Deemed to be University), Chennai 600 119, Tamil Nadu, IndiaCentre for Molecular and Nanomedical Sciences, International Research Centre, Sathyabama Institute of Science and Technology (Deemed to be University), Chennai 600 119, Tamil Nadu, India; School of Bio and Chemical Engineering, Department of Biotechnology, Sathyabama Institute of Science and Technology (Deemed to be University), Chennai 600 119, Tamil Nadu, IndiaCentre for Molecular and Nanomedical Sciences, International Research Centre, Sathyabama Institute of Science and Technology (Deemed to be University), Chennai 600 119, Tamil Nadu, India; School of Bio and Chemical Engineering, Department of Biotechnology, Sathyabama Institute of Science and Technology (Deemed to be University), Chennai 600 119, Tamil Nadu, IndiaCentre for Molecular and Nanomedical Sciences, International Research Centre, Sathyabama Institute of Science and Technology (Deemed to be University), Chennai 600 119, Tamil Nadu, India; School of Bio and Chemical Engineering, Department of Biotechnology, Sathyabama Institute of Science and Technology (Deemed to be University), Chennai 600 119, Tamil Nadu, IndiaSchiff bases are formed through the condensation of primary amines with aldehydes or ketones. Due to their simple synthesis and versatile properties, they are highly favored as ligands in coordination chemistry. They are widely applied in fields such as biology, industry, food packaging, dyes, polymers, and oxygen detectors. Schiff base ligands are crucial in forming transition metal complexes, which serve as precursors for synthesizing metal and metal chalcogenide nanoparticles. Organic Fluorophore Schiff bases containing fluorophore groups have gained attention for their enhanced photophysical properties and broad pharmacological activities. Their metal complexes are efficient in catalyzing organic oxidation reactions. The structural diversity and ability to chelate metals make these compounds highly adaptable for various applications. This review explores the preparation, physical, biological properties, and catalytic applications of Organic Fluorophore Schiff bases metal complexes for biomedical applications.http://www.sciencedirect.com/science/article/pii/S2211715625001493AnthraceneCoumarinFluoresceinNaphthaleneSchiff BasePhotophysical properties
spellingShingle Mani Rajasekar
Jennita Mary
Meenamigai Sivakumar
Showparnickaa Subburao Ravichandran
Dharshini Srinivasan
Recent advances in organic fluorophore-based Schiff base metal complexes: Applications in biomedicine and related fields
Results in Chemistry
Anthracene
Coumarin
Fluorescein
Naphthalene
Schiff Base
Photophysical properties
title Recent advances in organic fluorophore-based Schiff base metal complexes: Applications in biomedicine and related fields
title_full Recent advances in organic fluorophore-based Schiff base metal complexes: Applications in biomedicine and related fields
title_fullStr Recent advances in organic fluorophore-based Schiff base metal complexes: Applications in biomedicine and related fields
title_full_unstemmed Recent advances in organic fluorophore-based Schiff base metal complexes: Applications in biomedicine and related fields
title_short Recent advances in organic fluorophore-based Schiff base metal complexes: Applications in biomedicine and related fields
title_sort recent advances in organic fluorophore based schiff base metal complexes applications in biomedicine and related fields
topic Anthracene
Coumarin
Fluorescein
Naphthalene
Schiff Base
Photophysical properties
url http://www.sciencedirect.com/science/article/pii/S2211715625001493
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